Regenerative Medicine - from Protocol to Patient
Overview
- Editors:
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Gustav Steinhoff
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Department of Cardiac Surgery, University of Rostock, Rostock, Germany
- Basic molecular mechanisms of human stem cell differentiation
- Molecular mechanisms and technologies for (re-)programming
- Analytical methods to classify stem cell fate and function
- Specific features of different human stem cell types
- Physiology and pathology of stem cells
- Includes supplementary material: sn.pub/extras
About this book
Regenerative medicine is the main field of groundbreaking medical development and therapy using knowledge from developmental and stem cell biology as well as advanced molecular and cellular techniques. This collection of volumes, Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. International leading experts from all over the world describe the latest scientific and clinical knowledge of the field of regenerative medicine. The process of translating science of laboratory protocols into therapies is explained in sections on regulatory, ethical and industrial issues. The collection is organized into five volumes: (1) Biology of Tissue Regeneration, (2) Stem Cell Science and Technology, (3) Tissue Engineering, Biomaterials and Nanotechnology, (4) Regenerative Therapies I, and (5) Regenerative Therapies II. The textbook gives the student, the researcher, the health care professional, the physician and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practiced therapies in regenerative medicine.
Volume 3: Tissue engineering, Biomaterials and Nanotechnology focuses the development of technologies, which enable an efficient transfer of therapeutic genes and drugs exclusively to target cells and potential bioactive materials for clinical use. Principles of tissue engineering, vector technology, multifunctionalized nanoparticles, biodegradable materials, controlled release, and biointerface technology are described with regard to the development of new clinical cell technology. Imaging and targeting technologies as well as biological aspects of tissue and organ engineering are depicted.
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Table of contents (9 chapters)
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Front Matter
Pages i-xiii
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- Maurizio Pesce, Rosaria Santoro
Pages 1-12
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- Ottmar Herchenröder, Julia Reetz, Brigitte M. Pützer
Pages 13-40
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- Timothy J. Nelson, Almudena Martinez-Fernandez, Satsuki Yamada, Andre Terzic
Pages 41-64
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- Michael Schroeter, Britt Wildemann, Andreas Lendlein
Pages 65-96
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- Naresh Polisetti, Geeta K. Vemuganti, May Griffith
Pages 97-122
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- Jie Zhou, Changyou Gao, Wenzhong Li
Pages 123-150
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- Bita Sedaghati, Jan Hoyer, Achim Aigner, Michael C. Hacker, Michaela Schulz-Siegmund
Pages 185-210
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- Cajetan Lang, Sebastian Lehner
Pages 211-240
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Back Matter
Pages 241-244
Editors and Affiliations
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Department of Cardiac Surgery, University of Rostock, Rostock, Germany
Gustav Steinhoff
About the editor
Gustav Steinhoff initiated and leads the Reference and Translation Center for Cardiac Stem Cell Therapy (RTC) of the University Medical Center Rostock. He is known as an expert in the medical field of stem cell therapies and the first clinician to treat patients with intramyocardial transplantation of purified stem cells and is one of the pioneers of these new therapies. Besides his medical study at the Erasmus University Rotterdam, Gustav Steinhoff performed research at the Baylor College in Houston, Texas. He has worked as a surgeon at the University of Kiel and the Medical School Hannover, where he was appointed as an Associate Professor of Cardiothoracic Surgery in 1998. In 2000 he moved to the University of Rostock as a Director and Chairman of the Department of Cardiac Surgery where he continued his research on cardiac stem cell therapies and tissue engineering.