Overview
- Provides a review of historical development of ideas in cellular ageing and replicative senescence
- Presents a discussion of ageing and cancer in cell proliferation regulation
- Explains usage of the cellular ageing model system for testing ageing modulators or anti-ageing compounds
- Offers practical suggestions for future research and development in human health and disease
- Includes supplementary material: sn.pub/extras
Part of the book series: Healthy Ageing and Longevity (HAL)
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About this book
Cellular Ageing and Replicative Senescence is organized into five sections: history and origins; serial passaging and progressive ageing; cell cycle arrest and senescence; system modulation; and recapitulation and future expectations. These issues are discussed by leading thinkers and researchers in biogerontology and cytogerontology. This collection of articles provides state-of-the-art information, and will encourage students, teachers, health care professionals and others interested in the biology of ageing to explore the fascinating and challenging question of why and how our cells age, and what can and cannot be done about it.
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Keywords
Table of contents (17 chapters)
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History and Origins
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Serial Passaging and Progressive Changes
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Ageing, Cancer and Senescence
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Ageing Modulators
Editors and Affiliations
Bibliographic Information
Book Title: Cellular Ageing and Replicative Senescence
Editors: Suresh I.S. Rattan, Leonard Hayflick
Series Title: Healthy Ageing and Longevity
DOI: https://doi.org/10.1007/978-3-319-26239-0
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2016
Hardcover ISBN: 978-3-319-26237-6Published: 17 May 2016
Softcover ISBN: 978-3-319-79912-4Published: 26 May 2018
eBook ISBN: 978-3-319-26239-0Published: 09 May 2016
Series ISSN: 2199-9007
Series E-ISSN: 2199-9015
Edition Number: 1
Number of Pages: VIII, 364
Number of Illustrations: 9 b/w illustrations, 18 illustrations in colour
Topics: Cytogenetics, Cell Biology, Geriatrics/Gerontology