Overview
- Discusses issues unique to rare diseases
- Written by a group of international expert authors
- Discusses mechanisms, manifestations, and clinical outcomes
- Includes supplementary material: sn.pub/extras
Part of the book series: Respiratory Medicine (RM)
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About this book
This book offers a comprehensive overview of alpha-1 antitrypsin deficiency, an inherited condition that leads to lung disease in adults and liver disease in adults and children and is associated with chronic obstructive lung disease in adults. While it is a rare condition, the mechanisms underlying the clinical manifestations of this deficiency have been largely clarified. Treatment, however, is available only for the lung disease that arises from the condition, thus necessitating continued research into new and alternative therapeutic solutions. The book discusses the biology of alpha-1 antitrypsin, protein misfolding and polymerization, and diagnosis and treatment of alpha-1 antitrypsin deficiency and its associated diseases. It concludes with a discussion of rare disorders linked to alpha-1 antitrypsin deficiency and the role of healthcare organizations in the treatment of these diseases. Written for pulmonary clinicians and scientists, Alpha-1 Antitrypsin: Role in Health and Disease is a valuable resource that sheds light on this rare disease.
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Keywords
Table of contents (9 chapters)
Editors and Affiliations
About the editors
Adam Wanner, MD
Division of Pulmonary and Critical Care Medicine
Miller School of Medicine
University of Miami
Miami, FL, USA
Robert A. Sandhaus, MD, PhD
Division of Pulmonary, Critical Care, and Sleep Medicine
National Jewish Health
Denver, CO, USA
Bibliographic Information
Book Title: Alpha-1 Antitrypsin
Book Subtitle: Role in Health and Disease
Editors: Adam Wanner, Robert A. Sandhaus
Series Title: Respiratory Medicine
DOI: https://doi.org/10.1007/978-3-319-23449-6
Publisher: Humana Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer International Publishing Switzerland 2016
Hardcover ISBN: 978-3-319-23448-9Published: 06 January 2016
Softcover ISBN: 978-3-319-79484-6Published: 30 March 2018
eBook ISBN: 978-3-319-23449-6Published: 18 December 2015
Series ISSN: 2197-7372
Series E-ISSN: 2197-7380
Edition Number: 1
Number of Pages: X, 173
Number of Illustrations: 15 b/w illustrations, 12 illustrations in colour
Topics: Pneumology/Respiratory System