Overview
- Covers groundbreaking research into new understandings and uses for older and well-known enzymes
- Explores both human and mosquito lysozymes and their medical potential
- Considers the potential role of other antimicrobial peptides, ie TEP-1 in the mosquito, and PF-4 in the human host
- Includes supplementary material: sn.pub/extras
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About this book
Malaria remains an alarming emergency in developing countries. It is thus urgent to identify any parasite or host molecules that can serve as new affordable markers for early diagnosis of disease complications or as new targets for vector control. In this context, human and mosquito lysozymes are good candidate molecules, as their involvement in malaria has been recently reported by several independent groups. This book reviews the grounded knowledge on malaria etiology and physiopathology, as well as the current approaches for diagnosis, therapy, and vector control. In addition, the emerging evidence on the involvement of human and mosquito lysozymes in malaria from available experimental models and clinical studies is thoroughly discussed, as is the potential use of other antimicrobial peptides against malaria. Intriguingly, the contributors propose that old well-known molecules such as lysozymes might be used as new targets for cost-effective strategies to fight malaria.
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Table of contents (7 chapters)
Editors and Affiliations
About the editor
Mauro Prato currently works as an Adjunct Professor of Biochemistry at the University of Torino, Italy. His research activity focuses on the involvement of proteolytic enzymes in malaria. His track-record includes 40 papers published by peer-reviewed journals, 1 book, 7 book chapters, 97 communications in well-established conferences, and 1 patent.
Bibliographic Information
Book Title: Human and Mosquito Lysozymes
Book Subtitle: Old Molecules for New Approaches Against Malaria
Editors: Mauro Prato
DOI: https://doi.org/10.1007/978-3-319-09432-8
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing Switzerland 2015
Hardcover ISBN: 978-3-319-09431-1Published: 04 November 2014
Softcover ISBN: 978-3-319-38089-6Published: 23 August 2016
eBook ISBN: 978-3-319-09432-8Published: 16 October 2014
Edition Number: 1
Number of Pages: IX, 108
Number of Illustrations: 5 b/w illustrations, 16 illustrations in colour
Topics: Parasitology, Medical Microbiology, Immunology