Overview
- Focused on endotoxic shock and on specific clinical aspect and medical clinical management of endotoxemia
- Highlights clinical management of endotoxic shock according to conventional therapies
- Points out clinical management of endotoxic shock according to complementary therapies
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About this book
This book provides easy consultation and guidance for an appropriate understanding and management of endotoxic shock. Endotoxic shock results from a severe, generalized inflammatory response induced by bloodstream infection with gram-negative bacteria. However, endotoxin-induced inflammatory activation may be disconnected by Gram-Negative threats (e.g. Gram-Positive and yeast infections) as well as occur in multiple clinical scenarios like post-cardiac arrest syndrome and trauma, possibly due to gut barrier dysfunction and consequent endotoxin translocation.
The clinical management is structured focusing and dedicating a chapter for antibiotics, corticosteroids, volume support, vasoactive and cardiostimulating drug, coagulopathy and nutritional support. In addition, this book is remarkable because describing polymixin b hemoperfusion points out molecular interactions, and hydrodynamics of Sorption.
Each section includes •) brief pathophysiology; •) principles of management; •) key messages. Readers can find updated tips related to the diagnosis and management of endotoxic shock with a multidisciplinary approach drawing a pathway from endotoxin structure and source and the related pathophysiology of endotoxic shock underling the specific clinical aspect and focusing on medical clinical management of endotoxemia and extracorporeal removal.
The book – written by international opinion leaders of this field – is addressed to healthcare providers working in intensive care and represents a point of reference for intensivists, infectious disease physicians, nephrologists and critical care nurses involved in the management of endotoxic shock and enriched with useful downloadable material.Similar content being viewed by others
Keywords
Table of contents (14 chapters)
Editors and Affiliations
About the editors
Gianluca Villa is Associated Professor in Anaesthesiology, Intensive Care and Pain Medicine at the University of Florence. He is alsoa clinical researcher in Acute Kidney Injury and Extracorporeal Organ Support at International Renal Research Institute of Vicenza. Principal investigator of the International registry on Acute Renal Replacement Therapy (Global-ARRT Registry).
Bibliographic Information
Book Title: Endotoxin Induced-Shock: a Multidisciplinary Approach in Critical Care
Editors: Silvia De Rosa, Gianluca Villa
DOI: https://doi.org/10.1007/978-3-031-18591-5
Publisher: Springer Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2023
Hardcover ISBN: 978-3-031-18590-8Published: 13 January 2023
Softcover ISBN: 978-3-031-18593-9Published: 13 January 2024
eBook ISBN: 978-3-031-18591-5Published: 12 January 2023
Edition Number: 1
Number of Pages: VII, 133
Number of Illustrations: 19 illustrations in colour
Topics: Internal Medicine, Intensive / Critical Care Medicine, Nephrology