Overview
- Focuses on the fundamentals and applications of messenger RNA (mRNA)-based therapeutics
- Discusses the strengths and key challenges of this emerging class of drugs
- Provides a state-of-the-art overview on the emerging field of mRNA therapeutics
Part of the book series: RNA Technologies (RNATECHN, volume 13)
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About this book
This new book in the RNA Technologies series provides a state-of-the-art overview on the emerging field of mRNA therapeutics covering essential strategies for formulation, delivery, and application. It also reviews the promising role in cancer immunotherapy, respiratory diseases, and chronic HBV infection and discusses RNA vaccines in light of the current COVID-19 pandemic. mRNA-based approaches have great potential to revolutionize molecular biology, cell biology, biomedical research, and medicine. Thus, this handbook is an essential resource for researchers in academia and industry contributing to the development of this new area of therapeutics.
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Keywords
Table of contents (19 chapters)
Editors and Affiliations
About the editors
Jan Barciszewski is Professor at Adam Mickiewicz University (AMU) in Poznań, Poland and at the Institute of Bioorganic Chemistry of the Polish Academy of Sciences, Poznań, Poland where he has worked since 1974. He studied organic chemistry at the AMU. During his Ph.D. studies, he worked on the structure and function of modified bases and nucleoside sequences of plant phenylalanine specific transfer ribonucleic acid (tRNA), including cytokinins. He was subsequently granted Doctor of Science degree for his work on the properties of plant tRNAs and aminoacyl-tRNA synthetases. In the 1990s, he began working on the diagnosis and therapy of brain tumors. He developed a new method for the transformation of plant mitochondria based on catalytic RNAs and is currently involved in studies on a new type of catalytic RNAs (enantiomeric ribozymes) for efficient RNA target cleavage in vivo, as well as the search for new anti-aging agents.
Bibliographic Information
Book Title: Messenger RNA Therapeutics
Editors: Stefan Jurga, Jan Barciszewski
Series Title: RNA Technologies
DOI: https://doi.org/10.1007/978-3-031-08415-7
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022
Hardcover ISBN: 978-3-031-08414-0Published: 21 September 2022
Softcover ISBN: 978-3-031-08417-1Published: 22 September 2023
eBook ISBN: 978-3-031-08415-7Published: 20 September 2022
Series ISSN: 2197-9731
Series E-ISSN: 2197-9758
Edition Number: 1
Number of Pages: XII, 446
Number of Illustrations: 11 b/w illustrations, 57 illustrations in colour
Topics: Human Genetics, Medicinal Chemistry, Biomaterials, Cancer Research