Overview
- Investigates in vivo modeling and preclinical testing of intraperitoneally applied drugs
- Contains detailed protocols, ready for the lab
- Includes tips on troubleshooting and avoiding known pitfalls
Part of the book series: Methods in Molecular Biology (MIMB, volume 1049)
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About this book
Ovarian cancer is the most lethal malignancy of the female reproductive system and is also the fifth leading cause of cancer death in women. Sharing common characteristics of cancer, ovarian malignancy possess several clinical and biological particularities In Ovarian Cancer: Methods and Protocols, expert researchers in the field provide methods that have been created or adapted to study various aspects of ovarian cancer. These methods and techniques are applicable to study genetic alterations present in ovarian cancer, structural and metabolic features of ovarian cancer cells, include in vitro and in vivo models that recapitulate ovarian cancer development and progression, and describe ovarian cancer-oriented drug delivery approaches. Methodological chapters are grouped into seven thematic parts, any of them is introduced by short subject review. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Ovarian Cancer: Methods and Protocols seeks to aid scientist to optimize study designs, to correctly select the most applicable methods, and to produce interesting and novel results.
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Keywords
Table of contents (37 protocols)
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Evaluation of Genomic Alteration
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Targeted Analysis of DNA Methylation
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Gene/Genome Expression Assessing
Editors and Affiliations
Bibliographic Information
Book Title: Ovarian Cancer
Book Subtitle: Methods and Protocols
Editors: Anastasia Malek, Oleg Tchernitsa
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-62703-547-7
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, New York 2013
Hardcover ISBN: 978-1-62703-546-0Published: 03 August 2013
Softcover ISBN: 978-1-4939-5962-4Published: 23 August 2016
eBook ISBN: 978-1-62703-547-7Published: 04 August 2013
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XIV, 515
Number of Illustrations: 36 b/w illustrations, 47 illustrations in colour
Topics: Cancer Research, Oncology