Overview
- Provides an easily accessible reference volume for peptide microarrays experiments written by leading researchers in the field
- Details the process of turning biological observations into a high-throughput screening methodology
- Covers a wide range of peptide microarrays formats and protocols
- Presents a modular approach to experimental design, screening modalities, detection technologies, and approaches to data analysis
- Comprehensive guide to developing, running, and analyzing peptide microarrays
Part of the book series: Methods in Molecular Biology (MIMB, volume 570)
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About this book
Due to their versatility, along with the diminishing costs of library synthesis and the growth of commercial support, peptide microarrays will likely expand beyond being just a research tool into an adaptable and powerful platform to be harnessed for wider drug discovery and point-of-care applications. In Peptide Microarrays: Methods and Protocols, experts in the field provide a cutting-edge view of peptide array technology, its applications, and technical issues. After examining how peptides can characterize proteins and clarify, at the amino acid level, the molecular recognition events in which they are involved, the volume goes on to cover topics such as the production and use of peptide arrays for enzyme and binding motifs characterization, epitope mapping, and diagnostics, the newest technological advancements, as well as software and web tools for the design of peptide arrays and for the analysis of output data. As a volume in the highly successful Methods in Molecular Biology™ series, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.
Authoritative and easy-to-use, Peptide Microarrays: Methods and Protocols promises to serve scientists with its unique insights and novel solutions in peptide array technology in order to advance this vital field.
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Keywords
Table of contents (24 protocols)
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Introduction
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Applications
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Technological Advancements
Editors and Affiliations
Bibliographic Information
Book Title: Peptide Microarrays
Book Subtitle: Methods and Protocols
Editors: Marina Cretich, Marcella Chiari
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-60327-394-7
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Humana Press 2009
Hardcover ISBN: 978-1-60327-393-0Published: 25 November 2009
Softcover ISBN: 978-1-61779-666-1Published: 07 March 2012
eBook ISBN: 978-1-60327-394-7Published: 31 July 2009
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XII, 434
Number of Illustrations: 116 b/w illustrations, 2 illustrations in colour
Topics: Protein Science, Biochemistry, general, Microarrays