Overview
- Editors:
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Jacques Banchereau
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Laboratory for Immunological Research, Schering-Plough, Dardilly, France
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Daniel Schmitt
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INSERM U346, Hôpital Edouard Herriot, Lyon, France
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About this book
These Proceedings contain the contributions of the partIcIpants of the Third International Symposium on Dendritic Cells that was held in Annecy, France, from June 19 to June 24, 1994. This symposium represented a follow-up of the first and second international symposia that were held in Japan in 1990 and in the Netherlands in 1992. Dendritic cells are antigen-presenting cells, and are found in all tissues and organs of the body. They can be classified into: (1) interstitial dendritic cells of the heart, kidney, gut, and lung;(2) Langerhans cells in the skin and mucous membranes; (3) interdigitating dendritic cells in the thymic medulla and secondary lymphoid tissue; and (4) blood dendritic cells and lymph dendritic cells (veiled cells). Although dendritic cells in each of these compartments are all CD45+ leukocytes that arise from the bone marrow, they may exhibit differences that relate to maturation state and microenvironment. Dendritic cells are specialized antigen-presenting cells for T lymphocytes: they process and present antigens efficiently in situ, and stimulate responses from naive and memory T cells in the paracortical area of secondary lymphoid organs. Recent evidence also demonstrates their role in induction of tolerance. By contrast, the primary and secondary B-cell follicles contain follicular dendritic cells that trap and retain intact antigen as immune complexes for long periods of time. The origin of follicular dendritic cells is not clear, but most investigators believe that these cells are not leukocytes.
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Table of contents (127 chapters)
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Dendritic Cells in Transplantation, Allergy and Oncology
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- Jan H. de Graaf, Gregor P. M. Mannes, Rienk Y. J. Tamminga, Willem A. Kamps, Wim Timens
Pages 535-537
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- J. M. Dobmeyer, T. S. Dobmeyer, R. E. Schopf
Pages 539-541
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- Lina Lu, Jacky Woo, Youping Li, Abdul S. Rao, Angus W. Thomson
Pages 543-548
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- Thierry Marchal, Colette Dezutter-Dambuyant, Corinne Fournel, Jean-Pierre Magnol, Daniel Schmitt
Pages 549-551
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- Sergiusz Markowicz, Jan Walewski, Andrzej Kawecki
Pages 553-555
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- A. J. Stagg, M. Breban, R. E. Hammer, S. C. Knight, J. D. Taurog
Pages 557-559
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- K. L. Summers, J. L. O’Donnell, P. B. Daniels, D. N. J. Hart
Pages 561-563
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Back Matter
Pages 571-572
Editors and Affiliations
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Laboratory for Immunological Research, Schering-Plough, Dardilly, France
Jacques Banchereau
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INSERM U346, Hôpital Edouard Herriot, Lyon, France
Daniel Schmitt