Overview
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1091)
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About this book
The field of Structural Genomics has produced many technological advances that transform and accelerate structure solution and analysis. Structural Genomics: General Applications emphasizes the benefits to the wider structural research community. It also reflects the current trend in tackling the more ambitious challenges of studying macromolecular machineries and complexes. Divided into three convenient sections, topics include the cloning and production of proteins for structural studies, experimental methods, and computational methods and data analysis. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.
Authoritative and easily accessible, Structural Genomics: General Applications aims primarily to channel spin-off technologies to the average structural biologist in a small or medium-sized laboratory.
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Keywords
Table of contents (24 protocols)
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Cloning, Expression and Protein Production
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Experimental Structure Determination and Characterization
Editors and Affiliations
Bibliographic Information
Book Title: Structural Genomics
Book Subtitle: General Applications
Editors: Yu Wai Chen
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-62703-691-7
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2014
Hardcover ISBN: 978-1-62703-690-0Published: 09 November 2013
Softcover ISBN: 978-1-4939-6060-6Published: 23 August 2016
eBook ISBN: 978-1-62703-691-7Published: 08 November 2013
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XV, 358
Number of Illustrations: 17 b/w illustrations, 63 illustrations in colour
Topics: Human Genetics, Proteomics