Abstract
The problem of variable cell survival probability along the spread-out Bragg peak is one of the long standing problems in planning and optimisation of ion-beam therapy. This problem is considered using the multiscale approach to the physics of ion-beam therapy. The physical reasons for this problem are analysed and understood on a quantitative level. A recipe of solution to this problem is suggested using this approach. This recipe can be used in the design of a novel treatment planning and optimisation based on fundamental science.
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Contribution to the Topical Issue “Dynamics of Systems at the Nanoscale”, edited by Andrey Solov’yov and Andrei Korol.
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Surdutovich, E., Solov’yov, A.V. Cell survival probability in a spread-out Bragg peak for novel treatment planning. Eur. Phys. J. D 71, 210 (2017). https://doi.org/10.1140/epjd/e2017-80120-0
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DOI: https://doi.org/10.1140/epjd/e2017-80120-0