Abstract
The Taylor dispersion technique has been used for measuring binary mutual diffusion coefficients for mixtures of 1,2,3,4-tetrahydronaphthalene (THN), isobutylbenzene (IBB) and dodecane (C12 H 26) at 0.5:0.5 mass fraction symmetric points, and for 0.9:0.1 mass fraction in IBB- C12 H 26. From the Stokes–Einstein equation and our experimental results, the limiting diffusion coefficients, D 0, and the equivalent solvated radii, R s, have been estimated at infinitesimal concentration of these species (TNH, IBB and C12 H 26). The measured diffusion coefficients are used to estimate activity coefficients of the components in the mixture, contributing to a better understanding of the structure of such systems and of their thermodynamic behaviour at different concentrations. We have also investigated the diffusion properties for a ternary system containing equal mass fractions of all the components (0.33THN: 0.33IBB: 0.33C12 H 26) and at 298.15 K.
Similar content being viewed by others
Avoid common mistakes on your manuscript.
Introduction
The Taylor dispersion technique is a fast and reliable method for the measurement of mutual diffusion coefficients (D ik) for binary and multicomponent solutions. It has been extensively tested for electrolytes and for dilute solutions e.g. Santos et al. (2015) and Ribeiro et al. (2011). Recently it has been extended to other systems of interest, such as the Fontainebleau benchmark mixture, which is a symmetrical mixture of 1,2,3,4-tetrahydronaphthalene (THN), isobutylbenzene (IBB) and dodecane (C12 H 26) at equal mass fraction (Gebhardt et al. 2013). This mixture is particularly important as it is widely used by the oil industry as a model (Shapiro et al. 2004) for understanding the thermodynamics inside hydrocarbon reservoirs during the exploration stage (Shapiro et al. 2004) This study is also motivated by the DCMIX program (Diffusion and Thermodiffusion Coefficients in Mixtures) of the European Space Agency (ESA), for which it was the first mixture investigated. Within the framework of this program (DCMIX1), experiments conducted on-board the International Space Station aim to measure the thermodiffusion effects in binary and ternary mixtures to validate results obtained on the ground, as reported in 2015 by Shevtsova et al. (2015), Mialdun et al. (2015), Galand and Van Vaerenbergh (2015), Ahadi and Saghir (2015) and Khlybov et al. (2015). Several international teams and laboratories have dedicated their work to the difficult task of establishing the isothermal diffusion coefficients for binary and ternary mixtures of these components. There is fair agreement between all the results reported in the literature, which have been obtained through various experimental methods, with deviations between them of the order of 8.5 % (Platten et al. 2003).
The main goal of this work is to adapt and optimize our Taylor dispersion equipment and protocol to the measurement of diffusion coefficients in the Fontainebleau benchmark mixture, which will provide additional trustworthy information on this benchmark mixture to the scientific community. This technique has established itself as a reliable experimental method for the determination of mutual diffusion coefficients in binary, ternary and even quaternary liquid systems (e.g. Santos et al. 2012, 2013, 2015; Ribeiro et al. 2006, 2010, 2011). For binary solutions, the usual procedure consists of the injection of a small volume of solution containing the solute at concentration c±Δc into a laminar carrier stream of composition c. As the injected sample flows through a long capillary tube, radial diffusion and convection along the tube axis shape the initial δ concentration pulse into a Gaussian profile. Binary mutual diffusion coefficients (D) are calculated from the broadened distribution of the dispersed sample measured at the tube outlet. This technique has been extended to measure ternary mutual diffusion coefficients (D ik) for multicomponent solutions. The results include diffusion cross-coefficients Dik (i ≠k) which describe the coupled fluxes of solutes driven by concentration gradients in the other. Studies for binary mixtures involving 1,2,3,4-tetrahydronaphthalene, isobutylbenzene and dodecane were made for 0.5–0.5 mass fraction symmetric points, and with IBB-C12H26 for 0.9:0.1 mass fraction . In case of ternary mixtures measures were made for liquids with equal mass fractions of all the components (0.33:0.33:0.33). The results obtained for all these systems at 298.15 K are presented in Tables 1 and 2.
Experimental
Materials
1,2,3,4-tetrahydronaphthalene (mass fraction purity 0.98, density 0.973 g cm −3) and isobutylbenzene (mass fraction purity 0.99, density 0.850 g cm −3) were supplied from Acros Organics. Dodecane (mass fraction purity 0.99, density 0.750 g cm −3), was supplied by Panreac Sinthesis. All liquids were used as received, with no further purification. Mixtures with various compositions were prepared by weighing each component using a Mettler H80 analytical balance with resolution 0.1 mg/160 g. Each mixture was freshly prepared and de-aerated for about 30 min before each set of runs.
Diffusion Measurements
The Taylor dispersion technique is well described in the literature as an experimental method for the measurement of diffusion coefficients, as in Tyrrel (1964), Barthel et al. (1996), Loh (1997), Alizadeh et al. (1980) and Callendar and Leaist (2006). Only a brief description of the equipment and procedure used in the present study is presented here (see Santos et al. 2012, 2013, 2015; Ribeiro et al. 2006, 2010, 2011).
The Taylor method is based on the dispersion of small amounts of solution injected into laminar carrier streams of solution of different composition flowing through a long capillary tube. At the start of each run, a 6-port Teflon injection valve (Rheodyne, model 5020) was used to introduce 63 mm 3 of solution into a laminar carrier stream of slightly different composition. A flow rate of 0.20 cm 3 min −1 was maintained by a metering pump (Gilson model Minipuls 3) to give retention times of about 1.1×104 s. The dispersion tube (length 32.799 (±0.001) m) and the injection valve were kept at 298.15 K in an air thermostat. Dispersion of the injected samples was monitored using a differential refractometer (Waters model 2410) at the outlet of the dispersion tube. Detector voltages, V(t), were measured at 5 s intervals with a digital voltmeter (Agilent 34401 A).
Binary diffusion coefficients were evaluated by fitting the detector voltages to the dispersion equation
where r is the internal radius of the dispersion tube. The additional fitting parameters were the mean sample retention time tR, peak height \(V_{\max }\), baseline voltage V0, and baseline slope V1.
Mutual diffusion in ternary solutions is described by the equations
where J1, J2, ∇c1, and ∇c2 are the molar fluxes and the gradients in the concentrations of solute 1 and 2, respectively. The main diffusion coefficients D11 and D22 give the flux of each solute produced by its own concentration gradient. Information about coupled diffusion is provided by cross-diffusion coefficients D12 and D21.A positive Dik cross- coefficient (i≠k) indicates co-current coupled transport of solute i from regions of higher to lower concentrations of solute k. A negative Dik coefficient indicates counter-current coupled transport of solute i from regions of lower to higher concentration of solute k.
The Dik coefficients, defined by Eqs. 2 and 3 were evaluated by fitting the ternary dispersion Eq. 4
The two pairs of refractive –index profiles, D1 and D2, are the eigenvalues of the matrix of the ternary Dik coefficients. W1 and 1−W1 are the normalized pre-exponential factors.
In these experiments, small volumes, ΔV, of the solution of composition c1±Δc1, c2±Δc2, are injected into carrier solutions of composition, c1 and c2 at time t=0. The concentrations of the injected solutions (c±Δc) and the carrier solutions (c), for both binary and ternary systems, differed by 10 % or less in mass. The mixtures in our experiments were prepared using mass fractions and later converted to molar concentrations (moles of solute per liter of solution) by means of the relation wi = ci(Mi/ρ) where wi stands for the concentration in mass fraction, ci is molar concentration, Mi is the molar mass of the constituent i and ρ the density of the mixture.
Details have previously been reported of the method of calculation of the Dik coefficients from the fitted values of D1, D2 and W1 by Deng and Leaist (1991). Following Legros et al. (2015), we have tested for the ternary mixture the smart strategy of tuning the injections so as to have the amplitude of one of the signals negative and obtain ‘double dip’ signals. The presence of these dissimilar shaped peaks demonstrates the existence of two modes, corresponding to different eigenvalues of the system, allowing to distinguishing between them and avoiding the selection of inaccurate solutions.
Results and Discussion
Tests of the Dispersion for Binary and Ternary Systems
The three possible binary mixtures (THN-IBB, IBB-C12 H26 and THN-C12 H26) at the 0.5:0.5 mass fraction symmetric points, and a fourth mixture THN-C12 H26 with 0.9:0.1 mass fraction, were used to test the operation of the dispersion equipment. These systems were chosen because their diffusion coefficients are accurately known from other experimental methods, as of Gebhardt et al. (2013) and Platten et al. (2003); the deviations between the results obtained from these techniques are, in general, less than 7 %, and at the most 8.5 %. The point 0.9:0.1 for THN-C12 H26 was also measured using the Taylor dispersion technique by Gebhardt et al. (2013) and provides possibilities for direct comparison. Taking these measurements as references, we have been able to adapt, optimize and build experimental protocol for our Taylor dispersion equipment which can be applied in the measurement of diffusion coefficients in the Fontainebleau benchmark mixture.
Table 1 gives the mean D values for four binary systems at 298.15 K determined from four to six replicate dispersion profiles. Comparative plots of our results with those previously published by Gebhardt et al. (2013), Platten et al. (2003) and Mialdun and Shevtsova (2011) for the same systems are shown on Fig. 1. Direct comparison of the results for the Taylor D values reported here, with D values obtained by other experimental methods, reveals that they are encompassed within the previously found 7 % uncertainty interval. If we consider that 1–3 % uncertainty is typical for Taylor dispersion measurements, as shown in previous reports for binary systems by Santos et al. (2012, 2013, 2015) and Ribeiro et al. (2006, 2010, 2011) this suggests an acceptable accuracy in these determinations.
The ternary diffusion coefficients measured for THN (1) + IBB (2) + C12 H26 (0) system are summarized in Table 2. The component zero is for the solvent. The main diffusion coefficients D11 and D22 were normally reproducible within ±0.08×10−9 m 2 s −1. The cross-coefficients were, in general, reproducible within about ±0.10×10−9 m 2 s −1. The results obtained for the mixtures under study are in reasonable agreement with available results in the literature, measured using Taylor dispersion, Counter Flow Cell and Sliding Symmetric Tubes techniques by Mialdun et al. (2013), Sechenyh et al. (2013) and Larrañaga et al. (2013). The ternary results obtained here differ only slightly from the published ones, and, although there is still no agreement on the actual values, the eigenvalues obtained from all the experiments are very close. Our eigenvalues differ between 3.5 and 8.8 % from those measured with the same experimental method. For the symmetric point under study there is one published result by Koninger et al. (2010), which was obtained by the Optical Beam Deflection technique in this system with a different order of the components (C12 H26 (1) + IBB (2) + THN (0)). Although this implies different values for the main and cross diffusion coefficients, the eigenvalues of the diffusion matrix do not depend on the order of the components, and the differences between our and the OBD published values are 17.8 % in \(\widehat {D}_{1}\) and 3.4 % in \(\widehat {D}_{2}\).
We can conclude from the non-zero cross diffusion coefficient values, Dij, at this finite concentration for the THN (1) + IBB (2) + C12 H26 (0) system, and by the fact that the main coefficients Dii are not the same as the binary diffusion ones, that there are solute interactions affecting the diffusion of the components, and, under these conditions, possible interactions between the solutes leads to a counter flow of IBB (D21<0). The gradient in the concentration of IBB produces co-current coupled flows of THN. If we consider that D12/ D22 values give the number of moles of THN co- transported per mole of IBB driven by its own concentration gradient, we can suggest that a mole of diffusing IBB co-transports 0.14 mol of THN at the concentration studied. From the D21/ D11 values, at the same compositions, we can anticipate that a mole of diffusing THN counter-transports 0.44 mol of IBB.
Diffusion: Useful Strategy for Structural Interpretation of Chemical Systems
Limiting Diffusion Coefficients and Radii of the Diffusing Entities
From the analysis of our D experimental data, together with literature diffusion coefficients at infinitesimal concentration, D 0 by Gebhardt et al. (2013), we can obtain structural information of the diffusing entities. The Stoke’s radii (r s) have been estimated using the Stokes Einstein equation (5), which assumes that the particles are perfectly spherical and are subject solely to solvent friction (Erdey-Grúz 1974)
where D 0 is the tracer diffusion coefficient of a species D 0 is the tracer diffusion coefficient of a species, and kB and η 0 are Boltzmann’s constant, and the solvent viscosity at temperature T (see Aminabhavi and Gopalakrishna 1995, Rathnam et al. 2010). As can be seen from Table 3, the different structures of these compounds lead us to obtain significant differences between their D 0 values that do not necessarily translate into changes in their Stokes radii. For example, for dodecane (C12 H 26) there is only a slight difference in its radius when the solvent is IBB or THN. Since the only possible interactions between these three molecules are Van der Waals and London dispersion forces, the smaller value obtained for C12 H 26 in THN is probably related to steric constraints on the accommodation of these molecules in the liquid phase.
Estimation of the Activity Coefficients
The inexistence of available vapor-liquid equilibrium data for the binary and ternary systems under study, as far as the authors know, constrains the calculation of activity coefficients. Therefore an alternative model for estimation of activity coefficients is presented ahead.
For non-ideal and non-dilute system of two components, Fick’s first law describes the flux that occurs in the system as a result of a drive to approach thermodynamic equilibrium. This flux is caused by gradients of chemical potential of the components rather than concentration, and for one-dimensional, isothermal, isobaric diffusion with no external potential gradients comes described by
where D is the diffusion coefficient, c is concentration, M ii are the coupling coefficients between fluxes and reflect the driving force of the flux and the mobility of the species in responding with movement, μ i is the chemical potential and z is the axis coordinate.
Introducing the definition of chemical potential for a given component
into Fick’s first law the expression for the flux is then:
where a i is the activity of component i, γ i is the activity coefficient of i,x i is the mole fraction of component i kB is Boltzmann’s constant and T stands for temperature.
If tracer diffusion coefficient that comes defined by Eq. 4, is the diffusion coefficient for ideal mixtures (where γ iis constant), rearranging Eq. 7 we have
where the parcel between brackets in normally called thermodynamic factor. By combining Eq. 8 with the one-parameter Margules (1895) activity model for a binary mixture of component 1 and component 2
activity coefficients can then be estimated from the molar fraction dependence of the ratio D/ D 0, considering through this approximation that variation in D is due to the variation of this thermodynamic factor.
The values thus obtained for the activity coefficients, γ, for the 3 different mixtures studied here are shown in Table 4. Data in Table 4 was obtained using molar fraction of the solutes in Eqs. 6–7; mass fraction information is present only for easier correlation with all other data. From the observed γ values for the system IBB/THN, we can say that in this particular mixture their components interact attractively toward each other and, consequently, this system is the one closest to the ideal solution, in contrast to what is observed for the other systems. That is, for C12 H 26/ IBB and C12 H 26/THN systems, the γ values reflect mixtures that are further away from ideality, mainly for extreme molar fractions of the components. This is an expected behaviour taking into account the steric constrains found when mixing two liquids composed with different shaped molecules, since it requires the rupture in the structure of the media.
Conclusions
Taylor dispersion equipment installed at the University of Coimbra for the measurement of diffusion in liquids has been tested to ensure in general an acceptable and adequate accuracy (2–5 %) by measuring mutual diffusion coefficients for binary aqueous solutions of systems.
Binary mutual diffusion coefficients for mixtures of THN, IBB and C12 H 26 at 0.5:0.5 mass fraction symmetric points, and for 0.9:0.1 mass fraction in IBB- C12 H 26 were measured with the Taylor dispersion technique. The results are in agreement with literature values and provide reliable support for data on this benchmark mixture.
Based on these measurements, it was possible, using appropriate models, to estimate transport, structural and thermodynamic parameters (D 0, radius and activity coefficients), which help us understand the nature and structure of these mixtures, which are important for practical applications in various fields, including the oil industry.
The ternary system containing equal mass fraction of all the components (0.33 THN- 0.33 IBB −0.33 C12 H 26) was also studied at 298.15 K. Good agreement was observed for both the diffusion coefficients and respective eigenvalues.
Our Taylor dispersion equipment has been successfully optimized and we were able to positively contribute with consistent isothermal diffusion data to characterization of the Fontainebleau benchmark mixture.
References
Ahadi, A., Saghir, M.Z.: Contribution to the benchmark for ternary mixtures: transient analysis in microgravity conditions. Eur. Phys. J. E, 38 (2015)
Alizadeh, A., Nieto de Castro C.A., Wakeham W.A.: The theory of the Taylor dispersion for technique for liquid diffusivity measurements. Int. J. Thermophys. 1, 243–284 (1980)
Aminabhavi, T.M., Gopalakrishna, B.: Densities, viscosities, and refractive indices of Bis(2-methoxyethyl) Ether + Cyclohexane or + 1,2,3,4-Tetrahydronaphthalene and of 2-Ethoxyethanol + Propan-1-ol, + Propan-2-ol, or + Butan-1-ol. J. Chem. Eng. Data 40, 462–467 (1995)
Barthel, J., Gores, H.J., Lohr, C.M., Seidl, J.J.: Taylor dispersion measurements at low electrolyte concentrations. I. Tetraalkylammonium perchlorate aqueous solutions. J. Solut. Chem. 25, 921–935 (1996)
Callendar, R., Leaist, D.G.: Diffusion coefficients for binary, ternary and polydisperse solutions from peak-width analysis of Taylor dispersion profiles. J. Solut. Chem. 35, 353–379 (2006)
Deng, Z., Leaist, D.G.: Ternary mutual diffusion coefficients of MgCl2+ MgSO4+ H2O and Na2 SO4+ MgSO4+ H2O from Taylor dispersion profiles. Can. J. Chem. 69, 1548–1553 (1991)
Erdey-Grúz, T.: Transport Phenomena in Aqueous Solutions, 2nd edn. Adam Hilger, London (1974)
Gebhardt, M., Köhler, W., Mialdun, A., Yasnou, V., Shevtsova, V.: Diffusion, thermal diffusion, and Soret coefficients and optical contrast factors of the binary mixtures of dodecane, isobutylbenzene, and 1,2,3,4-tetrahydronaphthalene. J. Chem. Phys. 138, 114503 (2013)
Galand, Q., Van Vaerenbergh, S.: Contribution to the benchmark for ternary mixtures: Measurement of diffusion and Soret coefficients of ternary system tetrahydronaphtalene-isobutylbenzene-n-dodecane with mass fractions 80-10-10 at 25 ∘C. Eur. Phys. J. E 38, 26 (2015)
Khlybov, A., Ryzhkov, I.I., Lyubimova, T.P.: Contribution to the benchmark for ternary mixtures: Measurement of diffusion and Soret coefficients in 1,2,3,4-tetrahydronaphthalene, isobutylbenzene, and dodecane onboard the ISS. Eur. Phys. J. E 38, 29 (2015)
Koninger, A., Wunderlich, H., Koher, W.: Measurement of diffusion and thermal diffusion in ternary fluid mixtures using a two-color optical beam deflection technique. J. Chem. Phys. 132, 174506 (2010)
Larrañaga, M., Bou-Ali, M.M., Soler, D., Martinez-Agirre, M., Mialdun, A., Shevtsova, V.: Remarks on the analysis method for determining diffusion coefficient in ternary mixtures. C. R. Mecanique 341, 356–364 (2013)
Legros, J.C., Gaponenko, Y., Mialdun, A., Triller, T., Hammon, A., Bauer, C., Kohler, W., Shevtsova, V.: Investigation of Fickian diffusion in the ternary mixtures of water–ethanol–triethylene glycol and its binary pairs. Phys. Chem. Chem. Phys. 17, 27713 (2015)
Loh, W.: Taylor dispersion technique for investigation of diffusion in liquids and its applications. Quim. Nova. 20, 541–545 (1997)
Margules, M. Sitzber. Akad. Wizz. Wien, Math. Naturw Klasse II 104, 1243–78 (1895)
Mialdun, A., Shevtsova, V.: Measurement of the Soret and diffusion coefficients for benchmark binary mixtures by means of digital interferometry. J. Chem. Phys. 134, 044524 (2011)
Mialdun, A., Sechenyh, V., Legros, J.C., Ortiz de Zárate, J.M., Shevtsova, V.: Investigation of Fickian diffusion in the ternary mixture of 1,2,3,4-tetrahydronaphthalene, isobutylbenzene, and dodecane. J. Chem. Phys. 139, 104903 (2013)
Mialdun, A., Legros, J.C., Yasnou, V., Sechenyh, V., Shevtsova, V.: Contribution to the benchmark for ternary mixtures: measurement of the Soret, diffusion and thermodiffusion coefficients in the ternary mixture THN/IBB/nC12 with 0.8/0.1/0.1 mass fractions in ground and orbital laboratories. Eur. Phys. J. E 38, 27 (2015)
Platten, J.K., Bou-Ali, M.M., Costeseque, P., Dutrieux, J.F., Kohlerk, W., Leppla, C., Wieg, S., Wittkok, G.: Benchmark values for the Soret, thermal diffusion and diffusion coefficients of three binary organic liquid mixtures. Phil. Mag. 83, 1965–1971 (2003)
Rathnam, M.V., Jain, K., Kumar, M.S.S.: Physical properties of binary mixtures of ethyl formate with Benzene, Isopropyl Benzene, Isobutyl Benzene, and Butylbenzene at (303.15, 308.15, and 313.15) K. J. Chem. Eng. Data 55, 1722–1726 (2010)
Ribeiro, A.C.F., Leaist, D.G., Esteso, M.A., Lobo, V.M.M., Valente, A.J.M., Santos, C.I.A.V., Cabral, A.M.T.D.P.V., Veiga, F.J.B.: Binary mutual Diffusion Coefficients of Aqueous Solutions of β-cyclodextrin at Temperatures from 298.15 to 312.15 K. J. Chem. Eng. Data 51, 1368–1371 (2006)
Ribeiro, A.C.F., Santos, C.I.A.V., Lobo, V.M.M.: Esteso M.A, Quaternary diffusion coefficients of β-cyclodextrin + KCl + caffeine + water at 298.15 K using a Taylor dispersion method. J. Chem. Eng. Data 55, 2610–2612 (2010)
Ribeiro, A.C.F., Gomes, J.C.S., Santos, C.I.A.V., Lobo, V.M.M., Esteso, M.A., Leaist, D.G.: Ternary mutual diffusion coefficients of aqueous NiCl2 + NaCl and NiCl2 + HCl solutions at 298.15 K. J. Chem. Eng. Data 56, 4696–4699 (2011)
Santos, C.I.A.V., Esteso, M.A., Sartorio, R., Ortona, O., Sobral, A.J.N., Arranja, C.T., Lobo, V.M.M., Ribeiro, A.C.F.: A comparison between the diffusion properties of Theophylline/ β-Cyclodextrin and Theophylline/2-Hydroxypropyl- β-Cyclodextrin in Aqueous Systems. J. Chem. Eng. Data 57, 1881–1886 (2012)
Santos, C.I.A.V., Ribeiro, A.C.F., Veríssimo, L.M.P., Lobo, V.M.M., Esteso, M.A.: Influence of potassium chloride on diffusion of 2-hydroxypropyl- β cyclodextrin and β-cyclodextrin at T = 298.15 K and T = 310.15 K. J. Chem. Thermodyn. 57, 220–223 (2013)
Santos, C.I.A.V., Esteso, M.A., Lobo, V.M.M., Cabral, A.M.T.D.P.V., Ribeiro, A.C.F.: Taylor dispersion technique as a tool for measuring multicomponent diffusion in drug delivery systems at physiological temperature. J. Chem. Thermodyn. 84, 76–80 (2015)
Sechenyh, V., Legros, J.C., Shevtsova, V.: Development and validation of a new setup for measurements of diffusion coefficients in ternary mixtures using the Taylor dispersion technique. C. R. Mecanique 341, 490–496 (2013)
Shapiro, A.A., Davis, P.K., Duda, J.L.: Diffusion in multicomponent mixtures. In: Gani, R., Kontogeorgis, G.K. (eds.) Computer aided property estimation. Elsevier, Amsterdam (2004)
Shevtsova, V., Gaponenko, Y.A., Sechenyh, V., Melnikov, D.E., Lyubimova, T., Mialdun, A.: Dynamics of a binary mixture subjected to a temperature gradient and oscillatory forcing. J. Fluid Mech. 767, 290 (2015)
Tyrrel, H.J.V.: The origin and present status of Fick’s diffusion law. J. Chem. Ed. 41, 397–400 (1964)
Acknowledgments
The authors are grateful for funding from the Coimbra Chemistry Centre, which is supported by the Fundação para a Ciência e a Tecnologia (FCT), Portuguese Agency for Scientific Research, through the programmes UID/QUI/UI0313/2013 and COMPETE. C.I.A.V.S. also thanks the FCT for support through Grant SFRH/BPD/92851/2013.
Author information
Authors and Affiliations
Corresponding authors
Additional information
This article belongs to the Topical Collection: Advances in Gravity-related Phenomena in Biological, Chemical and Physical Systems. Guest Editors: Valentina Shevtsova, Ruth Hemmersbach
Rights and permissions
About this article
Cite this article
Santos, C.I.A.V., Shevtsova, V., Burrows, H.D. et al. Optimization of Taylor Dispersion Technique for Measurement of Mutual Diffusion in Benchmark Mixtures. Microgravity Sci. Technol. 28, 459–465 (2016). https://doi.org/10.1007/s12217-016-9498-5
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12217-016-9498-5