Abstract
In order to solve this problem, a new biological detection method is proposed, which makes use of the characteristics of optical transmission at the edge of the spectral band gap and sensitive to refractive index variation. When the probe light with wavelength at the edge of the Bragg band gap of porous silicon is incident on the surface of porous silicon, the change of refractive index caused by deoxyribonucleic acid (DNA) reaction in porous silicon will affect the detection light intensity transmitted from the porous silicon sensor. By analyzing the change of the average gray value of the transmitted light image, the concentration of the DNA can be obtained.
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This work has been supported by the National Key R&D Program of China (No.2019YFC1606100), and by the National Natural Science Foundation of China (Nos.61665012, 61575168 and 11504313).
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Yang, J., Jia, Z., Lü, X. et al. Digital image biological detection technology based on the porous silicon periodic crystals film. Optoelectron. Lett. 17, 552–557 (2021). https://doi.org/10.1007/s11801-021-0176-5
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DOI: https://doi.org/10.1007/s11801-021-0176-5