Abstract
We discuss the estimation of the expected value of the quality-adjusted survival, based on multistate models. We generalize an earlier work, considering the sojourn times in health states are not identically distributed, for a given vector of covariates. Approaches based on semiparametric and parametric (exponential and Weibull distributions) methodologies are considered. A simulation study is conducted to evaluate the performance of the proposed estimator and the jackknife resampling method is used to estimate the variance of such estimator. An application to a real data set is also included.
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Tunes-da-Silva, G., Pedroso-de-Lima, A.C. & Sen, P.K. A semi-Markov multistate model for estimation of the mean quality-adjusted survival for non-progressive processes. Lifetime Data Anal 15, 216–240 (2009). https://doi.org/10.1007/s10985-008-9106-0
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DOI: https://doi.org/10.1007/s10985-008-9106-0