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Malignant Peripheral Nerve Sheath Tumor Arising from an Adrenal Ganglioneuroma in a 6-Year-old Boy

  • Case Report
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Pediatric and Developmental Pathology

Abstract

This report describes the youngest patient to develop a malignant peripheral nerve sheath tumor arising from a ganglioneuroma (MPNST ex Ganglioneuroma). The patient, a 6-year-old boy, was never irradiated and had no history or stigmata of neurofibromatosis. The report also includes a review of the previously published related cases, and an analysis of the immunohistochemistry and electron microscopy data available to date on the subject.

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Authors and Affiliations

  1. Department of Pathology and Laboratory Medicine, St. Christopher’s Hospital for Children, Erie Avenue at Front Street, Philadelphia, PA 19134, USA

    Jean-Pierre de Chadarévian, Judy Mae Pascasio & Christos D. Katsetos

  2. Department of Pediatrics, St. Christopher’s Hospital for Children, Philadelphia, PA 19134, USA

    Jean-Pierre de Chadarévian, Judy Mae Pascasio, Gregory E. Halligan & Christos D. Katsetos

  3. Department of Surgery, St. Christopher’s Hospital for Children, Philadelphia, PA 19134, USA

    Douglas A. Katz, Joseph A. Locono & Stephen Kimmel

  4. Section of Hematology/Oncology, St. Christopher’s Hospital for Children, Philadelphia, PA 19134, USA

    Gregory E. Halligan

  5. Drexel University College of Medicine, Philadelphia, PA, USA

    Jean-Pierre de Chadarévian, Judy Mae Pascasio, Gregory E. Halligan, Douglas A. Katz, Joseph A. Locono, Stephen Kimmel & Christos D. Katsetos

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  1. Jean-Pierre de Chadarévian
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  2. Judy Mae Pascasio
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  3. Gregory E. Halligan
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de Chadarévian, JP., Pascasio, J., Halligan, G. et al. Malignant Peripheral Nerve Sheath Tumor Arising from an Adrenal Ganglioneuroma in a 6-Year-old Boy. Pediatr. Dev. Pathol. 7, 277–284 (2004). https://doi.org/10.1007/s10024-004-8084-9

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  • DOI: https://doi.org/10.1007/s10024-004-8084-9

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