Summary and Conclusions
The effects of high spinal analgesia and hyperventilation on the incidence of epinephrine-provoked cardiac arrhythmias were reorded electrocardiographcally on dogs during anaesthesia with 1 per cent rnethoxyflurane and with 2 per cent halothane. It was obvious that neither spinal analgesia nor hyperventilation protects the heart of the dog from the potentially lethal effect of epinephrine when a stable level of anaesthesia is accomplished with methoxyflurane. During halothane anaesthesia, the epinephrine challenge is lethal in most instances.
Résumé
Les effets de l’analgésie rachidienne haute et de 1’hyperventilation sur la fréquence des arythmies cardiaques provoquées par T’épinéphrine ont été étudiés, chez des chiens soumis à l’anesthésie avec 1 pour cent de méthoxyflurane et 2 pour cent de fluothane, et, cela, sur un trace électrocardiographique. II s’est avéré que ni l’analgésie rachidienne, ni 1’hyperventilation, ne protège le cœur du chien contre l’effet mortel possible de l’épinéphrine, lorsque un plan stable d’anesthesié est obtenu avec le méthoxyflurane Au cours de l’anesthésie au fluothane, la tentative d’administrer de l’épinephrine est mortelle dans la plupart des cas.
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From the Anesthesia Research Laboratory, Department of Anesthesiology, State University of New York, Upstate Medical Centre, Syracuse, New York.
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Israel, J.S., Dobkin, A.B. & Robidoux, H.J. The effect of sympathetic blockade or hyperventilation on epinephrine-induced cardiac arrhythmias during anaesthesia with halothane and methoxyflurane. Can. Anaes. Soc. J. 9, 125–130 (1962). https://doi.org/10.1007/BF03021254
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DOI: https://doi.org/10.1007/BF03021254