Abstract
Duodenal motility was studied in diabetics with and without diarrhea. Diabetics with diarrhea had more and stronger pressure waves during fasting, more pressure waves after a test meal, and a total motor activity that was larger during fasting, after a test meal and after prostigmine. In addition, they had markedly more negative differential pressure waves in all periods, apparently because of a weaker reaction to intestinal distension. Maximal pressure appeared, on the average, shortly after the largest deflection in differential pressure. This difference was smallest in patients with diarrhea. An auxiliary finding was that the duration of action potential bursts increases after prostigmine.
Emphasis is placed on the importance of using a randomized, blind technic in evaluating the motility parameters registered, and, in addition, of employing in many cases, nonparametric statistical methods.
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Drewes, V.M. Mechanical and electrical activity in the duodenum of diabetics with and without diarrhea. Digest Dis Sci 16, 628–634 (1971). https://doi.org/10.1007/BF02239222
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DOI: https://doi.org/10.1007/BF02239222