Abstract
Porous biodegradable poly(urethanes) for reconstructing menisci have been prepared using two different combinations of techniques: freeze-drying/salt-leaching and in-situ polymerization/salt-leaching. Using these methods, homogenous porous materials with a controllable and reproducible morphology can be prepared. The materials were made of three different poly(urethanes): a methylenediphenyldiisocyanate-based polyurethane, a lysine diisocyanate-based poly(urethane), and a poly(ɛ-caprolactone)-based poly(urethane). The compressive stress-strain behavior of the Estane foams was determined. Foams made by the freeze-drying/salt-leaching technique implanted in dogs showed healing and good ingrowth of fibrocartilaginous tissue.
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References
Ghosh P, Taylor TKF (1987) Clinical Orthopeadics and Related Research 224:52–63
Ricklin P, Ruttiman A, Del Buono MS (1971) Meniscus Lesions. Georg Thieme Verlag, Stuttgart, pp 7–9
Veth RPH (1978) “On the results of meniscetomy of the knee”, Thesis, University of Groningen, The Netherlands
Jørgensen U, Sonne-Holm S, Lauridsen F, Rosenklint A (1987) J of Bone and Joint Surgery 69-B1(1):80–83
King D (1936) J Bone Joint Surg 18-A:333
Chadially FN, Wedge JH, van Lalende JMA (1986) J Bone Joint Surg 68-B:106
Webber JR, Harris HG, Hough Jr AJ (1985) J Orthop Res 3:36
Leenslag JW, Pennings AJ, Veth RPH, Nielsen HKL, Jansen HWB (1984) Macromol Chem Rapid Commun 5:815–821
Leenslag JW (1987) Poly(L-lactide) and its biomedical applications. Thesis University of Groningen, The Netherlands
Elema HA, de Groot JH, Nijenhuis AJ, Pennings AJ, Veth RPH, Jansen HWB (part 2, this journal)
Caplan AI (1984) Sci Am 4:82
Leenslag JW, Kroes MT, Pennings AJ, van der Lei B (1988) New Polymeric Materials 1:111
Bruin P, Veenstra GJ, Nijenhuis AJ, Pennings AJ (1988) Makromol Chem Rapid Commun 9:589
Klompmaker J, Veth RPH, Jansen HWB, Nijenhuis AJ, de Groot JH, Pennings AJ (accepted in Biomaterials)
Gogolewski S, Pennings AJ (1982) Makromol Chem Rapid Commun 3:839
Leenslag JW, Nijenhuis AJ, Pennings AJ, Veth RPH, Nielsen HKL, Jansen HWB (1986). Proceedings of the Noordwijkerhout, The Netherlands, pp 10/1–10/9
Saunders JH, Frisch KC (1964) Polyurethanes chemistry and technology, part 2. Interscience, New York, pp 4–7
Frisch KC, Saunders JH (1972) Plastic foams. Marcel Dekker, New York, pp 60–64
Smith P (1976) Thesis University of Groningen, The Netherlands
Hikmet RM, Callister S, Keller A (1988) Polymer 29:1378
Coudeville A, Eyharts P, Perinne JP, Rey L, Rouillard R (1981) J Vac Sci Technol 3:18
Aubert JH, Clough RL (1985) Polymer 26:2047
Szycher M, Porier VL, Dempsey DJ (1983) J Elastomers Plast 15:81
Rusch KC (1967) J Appl Polym Sci 13:2297
Doherty DJ, Hurd R, Lester GR (1962) Chem and Ind 30:1340
Gibson LJ, Ashby MF (1988) Cellular Solids, structure and properties. Pergamon Press, New York, pp 122–153
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de Groot, J.H., Nijenhuis, A.J., Bruin, P. et al. Use of porous biodegradable polymer implants in meniscus reconstruction. 1) Preparation of porous biodegradable polyurethanes for the reconstruction of meniscus lesions. Colloid & Polymer Sci 268, 1073–1081 (1990). https://doi.org/10.1007/BF01410672
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DOI: https://doi.org/10.1007/BF01410672