Summary
New methodology for the preparation of L-isoserine and its incorporation into N- and C-terminal position of peptides is described. Furthermore, the new protective group strategy allows regioselective functional group manipulation in multifunctional amino acids like serine and isoserine.
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Windeisen E (1993) Neue Typen biorelevanterα-funktioneller Carbonsäuren und ihre Verwendung zur Modifikation von Peptiden. Dissertation, TU München
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Windeisen, E., Pires, R., Heistracher, E. et al. New types of biorelevantα-functional carboxylic acids and their application for peptide modification. Amino Acids 8, 397–400 (1995). https://doi.org/10.1007/BF00806558
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DOI: https://doi.org/10.1007/BF00806558