Abstract
Unilateral hydrocephalus due to foramen of Monro-obstruction was diagnosed in a newborn who presented with macrocephaly at birth. The mother had mumps in the second trimester of pregnancy and immunological studies indicated possible intrauterine infection of the baby with mumps virus. His condition deteriorated rapidly, and he developed myoclonic seizures. The possible relationship of intrauterine mumps infection to neonatal neurological complications is discussed.
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Bray PF (1972) Mumps — a case of hydrocephalus? Pediatrics 49:446–448
Buynak EB, Whitman JE, Roehm RR, Morton EH, Lampson GM, Hilleman RM (1977) Comparison of neutralization and hemaglutination inhibition techniques for measuring mumps antibodies. Proc Soc Exp Biol Med 125:1068
Henle W (1969) Mumps virus. In: Lennete EH, Schmidt NJ (eds) Diagnostic procedures for viral and ricketsial infections. American Public Health Association Inc, New York, pp 457
Herndon RN, Johnson RT, Davis LE, Descalzi LR (1974) Ependymitis in mumps virus meningitis. Arch Neurol 30:475–479
Hollowach J, Thurston DL, Becker B (1957) Congenital defects in infants following mumps during pregnancy. J Pediatr 50:689–694
Hower J, Clar HE, Düchting M (1972) Occlusion of the aqueduct after mumps meningitis. Dtsch Med Wochenschr 97: 43–44
Johnson RT, Johnson KP (1968) Hydrocephalus following viral infection: The pathology of aqueductal stenosis developing after experimental mumps virus infection. J Neuropathol Exp Neurol 27: 591–605
Spitler LE (1976) Delayed hypersensitivity skin testing. In: Rose NE (ed) Manual of clinical immunology. ASM, Washington DC
London WT, Kent SG, Palmer AE, Fucillo DA, Houff SA, Saini N, Sever JL (1979) Induction of congenital hydrocephalus with mumps virus in rhesus monkeys. J Infect Dis 139:324–328
Rajapkase DA, Glyn LE (1970) Macrophage migration inhibition test using guinea pig macrophages and human lymphocytes. Nature (London) 226:857–858
Siegel M, Fuerst HT, Peress N (1966) Comparative fetal mortality in virus diseases. A prospective study on rubella, measles, mumps, chicken pox and hepatitis. N Engl J Med 274:768–771
St. Geme JW, Peralta H, Van Pelt LF (1972) Intrauterine infection of the rhesus monkey with mumps virus: Abbreviated viral replication in the immature fetus as an explanation for split immunologic recognition after birth. J Infect Dis 126: 249–255
Thompson JA, Glasgow LA (1980) Intrauterine viral infection and the cell-mediated immune response. Neurology 30:212–215
Timmons GD, Johnson KP (1970) Aqueductal stenosis and hydrocephalus after mumps encephalitis. N Engl J Med 283:1505–1507
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Baumann, B., Danon, L., Weitz, R. et al. Unilateral hydrocephalus due to obstruction of the foramen of monro: Another complication of intrauterine mumps infection?. Eur J Pediatr 139, 158–159 (1982). https://doi.org/10.1007/BF00441503
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DOI: https://doi.org/10.1007/BF00441503