Summary
Ten eyes of eight patients with pseudoexfoliation of the lens capsule were first studied by iris fluorescein angiography. Later, iris specimens were obtained at surgery and vessels that were newly formed or showed abnormally rich extravasation of fluorescein were studied electronmicroscopically.
The proliferated vessels had an abnormal basement membrane which was thin or absent, and there was abnormal extracellular material around the vessels. The endothelium was thin and in some cases fenestrae were observed. The electron-microscopic changes agreed with the rich extravasation of fluorescein from the capillaries seen in angiography.
The results show clearly that there are pronounced vascular changes in the anterior part of the eye in pseudoexfoliation. The way in which these changes affect the collection of pseudoexfoliation material in the eye requires further study.
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Vannas, A. Vascular changes in pseudoexfoliation of the lens capsule and capsular glaucoma. Albrecht von Graefes Arch. Klin. Ophthalmol. 184, 248–253 (1972). https://doi.org/10.1007/BF00413298
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DOI: https://doi.org/10.1007/BF00413298