Abstract
Ten rabbits underwent vitreous aspiration and replacement by either Healon® or Hydroxy Propyl Methyl Cellulose 2%. Four weeks' observation did not reveal noticeable differences between Healon and HPMC with regard to anterior chamber reaction, intra-ocular pressure or cataract. The vitreous reaction in eyes with HPMC was much more severe than in Healon eyes, with typical white precipitates and vitreous bands. Post-mortem examination confirmed the clinical findings.
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Aron-Rosa DS, Cohn HC, Aron JJ and Bonguety C (1983). Methylcellulose instead of Healon® in extracapsular surgery with intra-ocular lens implantation. Ophthalmology 90:1235–1238
Boyd BF (1982) What are significant contributions of CDS compared to Healon. Highlights Ophthal X/17:1–7
Denlinger JL and Balasz EA (1980). Replacement of the liquid vitreus with sodium hyaluronate in monkeyes. I. Short-term evaluation. Exp Eye Res 31:81–99
Denlinger JL, El-Mofty AAM and Balazs EA (1980) Replacement of the liquid vitreus with sodium hyaluronate in monkeys. II. Long-term evaluation. Exp Eye Res 31: 101–117
Deutman AF (1979) Experiences with different vitrectomy systems. Docum Ophthal 46:283–288
Draeger J and Winter R (1982) Kunstlinsen implantation unter Verwendung hochvisköser Hyaluronsäure. Klin Mbl Augenheilk 181:421–424
Fechner and Fechner MU (1983) Methylcellulose and lens implantation. Brit J Ophthal 67:259–263
Fitzgerald CR (1981) The use of Healon in a case of rolled-over retina. Retina 1:227–231
Françous J and Victoria-Troncoso V (1972/1973) Transplantation of vitreous cell culture. Ophthal Res 4:270–280
Laurent UBG (1981) Hyaluronate in aqueous humor. Exp Eye Res 33:147–155
MacRae SM, Edelhauser HF, Hyndiuk RA, Burd EM and Schultz RD (1983) The effects of sodium hyaluronate, chondroitin sulfate, and methylcellulose on the corneal endothelium and intraocular pressure. Amer J Ophthal 95:332–341
Michels RG (1981) Vitreous Surgery. St. Louis, Mosby, pp. 25–31
Mortada A (1982) Chemical vitrectomy: change of solid gel vitreous to sol for vitrectomy by changing pH of vitreous toward the slight acid side. Ann Ophthal 14: 465–469
Pallin SL and Walman GB (1981) Vitreous management during secondary implantation. Amer Intra-ocular Impknt Soc J 7:271
Schepens CL (1981) Clinical and research aspects of subtotal open-sky vitrectomy. Amer J Ophthal 91:143–171
Smith SG, Lindstrom RL, Miller RA, Hazel S, Skelnik D, Williams P and Mindrup E (1984) Safety and efficacy of 2% methylcellulose in cat and monkey cataract-implant surgery. Amer Intra-ocular Implant Soc J 10:160–163
Schmut O and Hofmann H (1982) Preparation of gels from hyaluronate solutions. Graefe's Arch Clin Exp Ophthal 218:311–314
Tolentino FI, Schepens CL and Freeman HM (1976) Vitreoretinal Disorders. Diagnosis and Management. Philadelphia, Saunders
Swann DA (1980) Chemistry of the vitreous body. Int Rev Exp Path 22:1–64
Zee van der WAM, Lean JS and Ryan SJ (1984) Unexpected retinal detachment: a complication of an animal model of pars plana vitrectomy. Graefe's Arch Clin Exp Ophthal 221:182–185
Zirm M (1982) Erste Erfahrungen mit Healon. Klin Mbl Augenheilk 181:425–428
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Koster, R., Stilma, J.S. Comparison of vitreous replacement with Healon® and with HPMC in rabbits' eyes. Doc Ophthalmol 61, 247–253 (1986). https://doi.org/10.1007/BF00142350
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DOI: https://doi.org/10.1007/BF00142350