Abstract
A direct immunological method by means of latex agglutination (LX) reaction was applied to the demonstration of Cryptosporidium oocysts from stools and gut homogenates. The LX method gave a positive diagnosis for all the specimens judged positive by the modified Ziehl-Neelsen technique, which served as a reference method, The results of the study indicate that the LX method can be adopted as a diagnostic tool for cryptosporidiosis, but further study concerning the specificity and sensitivity of the method is clearly warranted.
Sammendrag
En direkt immunologisk metod baserad på latex agglutinations (LX) reaktion tillämpades för att påvisa Cryptosporidium oocystor i avföring och tarmhomogen at. LX metoden gav positiv diagnos för alla preparat som också var positiva med modifierad Ziehl-Neelsen teknik, vilken fungerade som referensmetod. Resultaten visar att LX metoden kan användas vid diagnostik av kryptosporidios, men ytterligare studier med avseende på metodens specifitet och sensitivitet är nödvändiga.
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Pohjola, S., Neuvonen, E., Niskanen, A. et al. Rapid immunoassay for detection of Crypto-sporidium oocysts. Acta Vet Scand 27, 71–79 (1986). https://doi.org/10.1186/BF03548560
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DOI: https://doi.org/10.1186/BF03548560