Abstract
The kinetic parameters of the oxidation of a series of polyunsaturated fatty acids (PUFAs), linoleic and linolenic acids and ethyl esters thereof are determined by measuring the rate R OX of the process in chlorobenzene at 310 K. The selective replacement of H atoms by deuterium atoms results in a dramatic decrease in R OX (the H/D kinetic isotope effect, KIE). Furthermore, the addition of a deuterated PUFA to its nondeuterated analogue decreases R OX for the latter. It looks as if the deuterated PUFA partially protects nondeuterated one from oxidation. The information on the KIE obtained under conditions of initiated liquid-phase oxidation is reported in the current work for the first time; all the numerous previous reports have dealt with enzymatic oxidation.
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Original Russian Text © V.A. Roginskii, 2015, published in Khimicheskaya Fizika, 2015, Vol. 34, No. 5, pp. 18–22.
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Roginskii, V.A. Kinetic isotope effect in the oxidation of unsaturated fatty acids. Russ. J. Phys. Chem. B 9, 352–356 (2015). https://doi.org/10.1134/S1990793115030094
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DOI: https://doi.org/10.1134/S1990793115030094