Abstract
Three-dimensional computational models of the cerebrospinal fluid (CSF) flow and brain tissue are presented for evaluation of their hydrodynamic conditions before and after shunting for seven patients with non-communicating hydrocephalus. One healthy subject is also modeled to compare deviated patients data to normal conditions. The fluid-solid interaction simulation shows the CSF mean pressure and pressure amplitude (the superior index for evaluation of non-communicating hydrocephalus) in patients at a greater point than those in the healthy subject by 5.3 and 2 times, respectively.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
I. K. Pople, “Hydrocephalus and Shunts: What the Neurologist Should Know,” J. Neurology, Neurosurgery Psychiatry 73, i17–i22 (2002).
J. Malm, B. Kristensen, M. Fagerlund, et al., “Cerebrospinal Fluid Shunt Dynamics in Patients with Idiopathic Adult Hydrocephalus Syndrome,” J. Neurology, Neurosurgery Psychiatry 67, 273–277 (2009).
P. K. Eide and A. Brean, “Cerebrospinal Fluid Pulse Pressure Amplitude During Lumbar Infusion in Idiopathic Normal Pressure Hydrocephalus Can Predict Response to Shunting,” Cerebrospinal Fluid Res. 7 (5), (2010).
E. E. Jacobson, D. F. Fletcher, M. K. Morgan, and I. H. Johnston, “Computer Modelling of the Cerebrospinal Fluid Flow Dynamics of Aqueduct Stenosis,” Med. Biol. Engng Comput. 37, 59–63 (1999).
A. A. Linninger, M. Xenos, D. C. Zhu, et al., “Cerebrospinal Fluid Flow in the Normal and Hydrocephalic Human Brain,” IEEE Trans. Biomed. Engng. 54, 291–302 (2007).
B. Sweetman, M. Xenos, L. Zitella, and A. A. Linninger, “Three-Dimensional Computational Prediction of Cerebrospinal Fluid Flow in the Human Brain,” Comput. Biol. Med. 41, 67–75 (2011).
O. Algin, B. Hakyemez, and M. Parlak, “Phase-Contrast MRI and 3D-CISS Versus Contrast-Enhanced MR Cisternography on the Evaluation of Spontaneous Third Ventriculostomy Existence,” J. Neuroradiol. 38, 98–104 (2011).
S. Gholampour, N. Fatouraee, A. S. Seddighi, and S. Oraee Yazdani, “A Hydrodynamical Study to Propose a Numerical Index for Evaluating the CSF Conditions in Cerebral Ventricular System,” Intern. Clinical Neurosci. J. 1 (1), 1–9 (2014).
K. J. Streitberger, E. Wiener, J. Hoffmann, et al., “In Vivo Viscoelastic Properties of the Brain in Normal Pressure Hydrocephalus,” NMR Biomedicine 24 (4), 385–392 (2011).
Ö. Ünal, A. Kartum, S. Avcu, et al., “Cine Phase-Contrast MRI Evaluation of Normal Aqueductal Cerebrospinal Fluid Flow According to Sex and Age,” Diagnost. Intervent. Radiology 15, 227–237 (2009).
B. Siyahhan, V. Knobloch, D. de Ze’licourt, et al., “Flow Induced by Ependymal Cilia Dominates Near-Wall Cerebrospinal Fluid Dynamics in the Lateral Ventricles,” J. Roy. Soc. Interface 11, 20131189 (2014).
Author information
Authors and Affiliations
Corresponding author
Additional information
Original Russian Text © S. Gholampour, N. Fatouraee, A.S. Seddighi, A. Seddighi.
Translated from Prikladnaya Mekhanika i Tekhnicheskaya Fizika, Vol. 58, No. 3, pp. 12–18, May–June, 2017.
Rights and permissions
About this article
Cite this article
Gholampour, S., Fatouraee, N., Seddighi, A.S. et al. Numerical simulation of cerebrospinal fluid hydrodynamics in the healing process of hydrocephalus patients. J Appl Mech Tech Phy 58, 386–391 (2017). https://doi.org/10.1134/S0021894417030026
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S0021894417030026