Abstract
Purpose
To produce an experimental dense silica-based bioceramic composite added with nano-sized hydroxyapatite (HA) for biomedical application and physicochemical/ microstructurally characterize varying the firing temperature and the amount of binder, polyvinyl butyral (PVB).
Methods
Fumed SiO2 and nano-sized HA powder from bovine bone were ball milled aiming the mixture of powders. Groups were divided into HA (3, 5 and 10%), and PVB (1.2 and 2.4 wt.%) addition, and sintering process (1100, 1200 and 1300 °C with a 4 h plateau). The materials were characterized by X-ray Diffraction (XRD), Fourier Transform Infrared (FTIR) and Scanning Electron Microscopy (SEM) with Energy Dispersive X-ray Spectroscopy analysis (EDX).
Results
The group fired at 1200 °C presented potentialized chemical bonds without the degradation of HA at XRD profile, based on its microstructural evolution. FTIR spectra shows the degradation of HA, with an increase of CO2 band and a loss of the calcium-phosphate bands as the temperature increases. The binder concentration showed no chemical changes in the material. 2.4 wt.% of PVB addition resulted in optimized compaction and a lower inclusion of pores or cracks, suggested by SEM images.
Conclusion
This study suggests that the match composition of SiO2 matrix with 5% of HA and 2.4 wt.% of PVB, sintered at 1200 °C, exhibit potentially superior properties to biomaterial applications.
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Data Availability
All data are presented in the manuscript.
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Acknowledgements
The authors are grateful for the support provided by São Paulo Research Foundation (FAPESP) and the Coordination for the Improvement of Higher Education Personnel (CAPES).
Funding
This research was funded by São Paulo Research Foundation (FAPESP), grant number 2018/23639-0 and the Coordination for the Improvement of Higher Education Personnel (CAPES - Finance Code 001).
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All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by Brunna Mota Ferrairo, Victor Mosquim, Lucas José de Azevedo-Silva, Luara Aline Pires and David Santos Souza Padovini. The first draft of the manuscript was written by Brunna Mota Ferrairo. The manuscript was revised by Aroldo Geraldo Magdalena, Carlos Alberto Fortulan, Paulo Noronha Lisboa-Filho, José Henrique Rubo and Ana Flávia Sanches Borges. All authors read and approved the final manuscript.
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Ferrairo, B.M., Mosquim, V., de Azevedo-Silva, L.J. et al. Experimental Silica-based Bioceramic Composite Added with Nano-sized Bovine Hydroxyapatite: Synthesis and Characterization. Silicon 15, 7171–7181 (2023). https://doi.org/10.1007/s12633-023-02563-8
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DOI: https://doi.org/10.1007/s12633-023-02563-8