Abstract
In this study, silk fibroin (SF) was extracted from the silkworm cocoon and fabricated to form a nonwoven mat by electrospinning process. In order to improve the electrospinnability of SF, the polymer solution was treated with atmospheric pressure plasma. Conductivity and viscosity of SF-formic acid solution increased after the plasma treatment. The morphology of SF electrospun scaffolds before and after treatment was investigated by scanning electron microscope (SEM). The results showed that plasma treatment significantly improved the electrospinnability of SF solution and the morphology became fine and bead-less. Furthermore, the results of the fourier-transform infrared spectroscopy (FT-IR) and differential scanning calorimetry (DSC) showed that the plasma treatment increased the crystallinity of SF scaffolds and changed some part of polymer conformation from random coil to β-sheet crystals. Additionally, this method increased the mechanical properties and biodegradation resistance of SF scaffolds.
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Acknowledgements
This study was financially supported by the Amirkabir University of Technology (Tehran Polytechnic), Grant No. 95.
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Dadras Chomachayi, M., Solouk, A. & Mirzadeh, H. Improvement of the Electrospinnability of Silk Fibroin Solution by Atmospheric Pressure Plasma Treatment. Fibers Polym 20, 1594–1600 (2019). https://doi.org/10.1007/s12221-019-9015-8
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DOI: https://doi.org/10.1007/s12221-019-9015-8