Abstract
The secondary flow characteristics and the deposition of inhaled pollutants across the bifurcation ridge have been simulated using a control volume method for a three dimensional laminar inspiratory flow. For the present simulation, lower three generation human lung-airway from fifth to seventh branches is extracted following the Weibel’s model [1]. The extracted geometry is altered to create obstructions in order to study both symmetric and asymmetric form of Chronic Obstructive Pulmonary Disease (COPD). Computations are carried out for different particle diameters and number concentrations at Reynolds number (Re) of 1000 to replicate, understand and compare the physics of secondary flow in healthy and Asthma/ (COPD) affected human lung airway. Changes occurring in the the symmetric nature of secondary flow field, along and across the bifurcation ridge, arising due to various obstructions are profound. Mass flow rate imbalance, accumulation and newly generated vortices due to obstructions can be attributed to these changes.Further, the evolution of secondary vortices changes significantly due to inhaled pollutants where their deposition across the airways depends on their size and concentration.
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Jain, I., S.Sarkar (2023). CFD Analysis of Secondary Flow and Particle transportation in Human Lungs. In: Bhattacharyya, S., Chattopadhyay, H. (eds) Fluid Mechanics and Fluid Power (Vol. 1). FMFP 2021. Lecture Notes in Mechanical Engineering. Springer, Singapore. https://doi.org/10.1007/978-981-19-7055-9_31
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DOI: https://doi.org/10.1007/978-981-19-7055-9_31
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