Abstract
The micromixers are one of the significant elements in microfluidic applications, especially in lab-on-chip devices. In this paper, four split and recombine type micromixers are designed by altering the shape of the wall boundaries and inside grooves. The pressure drop and mixing of fluids in each micromixer are numerically analyzed, and results are compared for Reynolds number from 0.1 to 1. The mixing index is the maximum at Reβ=β0.1, and the value is almost the same for all the geometry. Results reveal that with the increase in Re, the mixing index decreases, and the pressure drop increases in each micromixer. Although micromixer with square inner grooves and triangular outer wall boundaries (SiTo) provides the best mixing, the associated pressure drop is also the highest. Thus, TiTo (micromixer with triangular inner and outer grooves) is recommended for mixing purposes. It provides second-highest mixing with comparatively lowest pressure drop than SiTo irrespective of the Reynolds number.
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1 Introduction
In this modern era, quick and uniform mixing is essential in various microfluidic areas such as LOC (lab on the chip) devices, Β΅-total analysis systems, biological and chemical synthesis [1,2,3,4]. In microfluidic devices, the mixing of fluids depends on molecular diffusion that reduces the mixing time of fluids due to laminar characteristics of flow. Various active and passive micromixers have been designed by several researchers with the purpose of increasing the mixing performance. Active micromixers require an external drive to generate energy for stirring the fluids to achieve fast mixing [1, 3,4,5], whereas in passive micromixers, mixing can be upgraded by designing or altering the geometries and shapes of the micromixers.
Several numerical and experimental studies have been performed in various micromixers as these micromixers are easy to fabricate by soft lithography techniques [6,7,8]. Mixing characteristics are analyzed in various micromixers by implementing various design concepts such as multiwave, square wave, zigzag, C-type, spiral contours. Channel walls are modified by ribs and grooves, placing the obstacles in the micromixers to disturb the flow are also introduced in order to enhance the mixing [9,10,11,12,13,14]. Sudarsan and Ugaz [15] considered planar split and recombine (S-R) and asymmetric serpentine micromixers to examine the mixing and flow characteristics of fluids. Both micromixers are found efficient in short downstream length. Hossain and Kim [16] analyzed mixing performance of water and ethyl alcohol in 3D serpentine S-R micromixer having special type segments (OH segments) and reported that SAR micromixer is more efficient than serpentine one. Hossain et al. [17] proposed an unbalanced three split rhombic sub-channel-based micromixer for studying the mixing and flow characteristics for 30ββ€βReββ€β80 and reported high mixing efficiency. Raza et al. [18] also used the concept of S-R in 3D serpentine micromixers with crossing channels by generating saddle type flow arrangement, which increases the chaotic advection even at low Reynolds numbers.
Numerous studies have been performed in S-R micromixers by various researchers. From the literature, it has been observed that nominal work has been done on different configurations of S-R geometry. In this paper, various types of S-R micromixers are designed by changing the shape of wall boundaries and inside grooves to examine the effect of shapes of S-R micromixers on the mixing performance of fluids in the micromixers. Mixing characteristics and pressure drop of mixing fluids are compared in these micromixers for low ranges of Re.
2 Problem Statement
First, a split and recombine (S-R) micromixer is designed having a square inner groove and square wall boundaries as shown in Fig.Β 1a, and the geometry is abbreviated as SiSo. Two fluids enter the micromixers in two opposite sides. The main width of the micromixers is 0.1Β mm. After traveling 0.5Β mm in the main mixing chamber, fluids split and again recombine in the square grooves-based chamber. Both width and depth of the outer square grooves are 0.2 mm whereas the width and depth of inner grooves are 0.1 mm. Eight such chambers are designed at 0.1Β mm distance. The exit length is 0.5Β mm. FigureΒ 1b represents the second S-R geometry (TiTo) with triangular inner grooves and triangular outer wall boundaries. FigureΒ 1c represents the S-R geometry (abbreviated as SiTo) in which the inner grooves are square and outer wall boundaries are triangular. The fourth micromixer (abbreviated as TiSo) is designed with triangular inner grooves and square outer wall boundaries. The sizes of all these grooves are taken exactly the same.
3 Mathematical Formulation
The velocity and pressure fields for a two-dimensional, steady-state, laminar, incompressible, isothermal, and single-phase flow in the micromixers are acquired using equations of continuity and Navier stokes for Newtonian fluids.
Here, \(\vec{U}\) is the velocity vector, Ο is the fluid density (kgΒ mβ3), P is pressure (Pa), \(\nu\) is kinetic viscosity of fluids (msβ2).
The concentration field is obtained by solving the species transport equation as follows:
Here, \({\complement }\) is the concentration of the species (mol-mβ3) and Ξ± is the coefficient of diffusion (m2Β sβ1).
Uniform inlet velocity and atmospheric pressure at the outlet and 0 slip boundary conditions at the walls are considered.
The mixing quality is quantified by the mixing index. It is determined by calculating the standard deviation of species in the perpendicular plane to the fluid flow. The standard deviation of the mass fraction of the fluid in any mixture at a cross-sectional plane is considered as
where SD is standard deviation of mass fraction in the particular cross-sectional area, r is overall number of sampling points, \(C_j\) is the mass fraction at sampling point j, and \(\overline{C_k }\) is average mixing mass fraction. After calculating the SD, the mixing index (MI) is calculated as
where \(\text{SD}_{\max }\) is the standard deviation of the completely unmixed state. It may be noted that the range of MI is 0 for fully unmixed fluids to 1 for fully mixed fluids.
4 Numerical Simulations
Numerical simulations are performed in Ansys-18.1 (Fluent). Water and water-dye solution are used as fluids for mixing. The viscosity of water is 0.9βΓβ10β3Β Pa-s and density is 1000Β kg/m3. The diffusion coefficient for water and water-dye solution is taken as 1.2βΓβ10β9Β m2/s. The SIMPLEC algorithm is applied for the pressure and velocity compounding. Second order upwind scheme is selected for discretization of the advection terms. For convergence, root mean square (RMS) residual is set as 10β5.
A detailed grid independency test is carried out to select the grid for actual simulation in order to minimize the computational cost and time without compromising the accuracy. A graph has been plotted (Fig.Β 2) between pressure drop and mixing index with the total number of elements for each micromixer configuration. From the graph, it is obvious that pressure drop and mixing index are constant after a certain value of elements. From the graph plot, grids with 326,903, 195,108, 328,959, and 354,679 number of elements are selected for SiSo, TiTo, SiTo, and TiSo micromixers, respectively, for further calculations.
To ensure the accuracy of adopted numerical methodology in the present work, the solver is validated by comparing the mixing index and pressure drop with the results reported in [19] for a T-shape micromixer as presented in Fig.Β 3. As shown in Fig.Β 3a, b obtained and published results are compared, and it shows that both results are approximately the same, which proves the authenticity of the simulation work.
5 Result and Discussion
The focus of the work is to analyze the effect of groove shapes on the mixing characteristics of fluids and pressure-drop in the split and recombine (S-R) microchannels for Reynolds number in the range of 0.1ββ€βReββ€β1. FigureΒ 4 represents the concentration contours of fluids at Reβ=β0.1 in each micromixer. Two fluids enter into the microchannel. For ideal mixing, the concentration plot should be uniform at the outlet of the channel throughout the cross-section. It is seen that at Reβ=β0.1, from chamber 3 onwards, almost green color appears, indicating the proper mixing in the channel. It is because of the low velocities of fluids at Reβ=β0.1, mixing or diffusion time to mix the fluids is more. FigureΒ 5 represents the concentration contours of fluids at Re = 0.6 in all the micromixers. Here, mixing is diminished than that of Reβ=β0.1 as when Re is increased to 0.6, the significant difference in the concentration can be seen in each micromixer. For Reβ=β1, the difference in the concentration increases more, as shown in Fig.Β 6. It indicates the lower mixing efficiency of the fluids at a higher Reynolds number. The trends of concentration contours in all the micromixers are almost the same with Re.
For the more comprehensive detail, streamlines distribution near the outlet in each micromixer is shown in Fig.Β 7 at Reβ=β1. Streamlines distribution are almost identical in SiSo and TiTo, as represented in Fig.Β 7a, b. It is clearly depicted that streamlines in SiTo (Fig.Β 7c) are closely packed near to the grooves, whereas in TiSo as shown in Fig.Β 7d, these streamlines maintain an almost equal distance from each other. This representation of streamlines in the microchannel shows the cause of different mixing indexes in the microchannel. Closely packed streamlines result in higher mixing than that of others.
The mixing index for different micromixers is compared at various Reynolds numbers in Fig.Β 8a. At Reβ=β0.1, the value of MI is the maximum, and it is almost the same for all the geometry. The change in the flow path has almost no influence because of the sufficient time for diffusion. It is observed that MI decreases with an increase in Re. It is due to a reduction in the diffusion mixing time with Re, and the homogeneity is completely diffusion controlled. The value of the mixing index is the highest in SiTo, whereas in TiSo, it is the lowest for Reββ₯β0.2. The values of the mixing index are almost the same for SiSo and TiTo micromixers, even for Reββ₯β0.2. The flow passages of two fluids in the micromixers are divided and again recombined and importantly, the shape of the groves modulates the same. In SiTo, more fluids come in contact because of the confined passage, and the fluids mixing takes place as it comes in contact more rapidly. That is why the mixing index in SiTo is more than that of other micromixers. On the other hand, in TiSo, fluids do not have enough contact to diffuse into each other, leading to the lower mixing index.
It is also vital to analyze the pressure drop in each micromixer. A pressure drop indicates the required driving force for fluid flow inside the micromixers. The pressure drop and Re graph for various micromixer geometry are demonstrated in Fig.Β 8b. From Fig.Β 8b, it is clear that the pressure drop increases with an increase in Re. The high value of Re means an increase in velocity that leads to the high-pressure drop irrespective of any geometrical parameters. On comparing, the pressure drop in different micromixer geometry for any values of Re, the pressure drop is the maximum in SiTo due to the more losses incurred in the flow as shown by the curvature of the streamlines (Fig.Β 7c). The difference of pressure drop between different configurations increases with Reynolds number.
6 Conclusion
In this present paper, pressure drop and flow characteristics are analyzed for two-dimensional, Newtonian, incompressible, steady flows in various split and recombine (S-R) micromixers. Four different configurations of micromixers are designed by considering the different shapes of grooves. The mixing characteristics and pressure drop for Re ranges from 0.1 to 1 are analyzed in the designed micromixers. The main outcomes of this research are concluded as:
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The mixing index reduces at higher Reynolds number in all the micromixers. At Reβ=β0.1, the mixing is the maximum, and the value is almost the same for all the geometry.
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The pressure drop increases with the Reynolds number for all the micromixers. Maximum pressure drop of 283Β Pa at Reβ=β1 and minimum of 28Β Pa at Reβ=β0.1 is observed in SiTo, whereas maximum pressure drop of 66Β Pa at Reβ=β1 and minimum of 6.7Β Pa at Reβ=β0.1 are observed in TiSo.
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The mixing quality is the highest in SiTo, whereas in TiSo, it is the lowest for Reββ₯β0.2. The mixing index values are approximately equal for SiSo and TiTo micromixers, even at Reββ₯β0.2.
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Even though SiTo shows highest mixing index but due to the high-pressure drop, it is not recommended whereas TiTo shows second-best mixing index and relatively much lower pressure drop in the channel than that of SiTo. Thus, TiTo could be used for industrial mixing purposes.
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Tripathi, E., Patowari, P.K., Pati, S. (2022). Numerical Investigations of Mixing Performance in Split and Recombine Micromixer. In: Kumar, S., Ramkumar, J., Kyratsis, P. (eds) Recent Advances in Manufacturing Modelling and Optimization. Lecture Notes in Mechanical Engineering. Springer, Singapore. https://doi.org/10.1007/978-981-16-9952-8_12
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