Zusammenfassung
Elektrophysiologische Messverfahren liefern objektive Befunde zur Funktion des somatosensorischen Systems. Mittels Elektroneurogramms (ENG) und somatosensorisch evozierter Potenziale (SEP) können die somatosensorischen Bahnen in ihrer gesamten Länge vom peripheren Nerv bis zum somatosensorischen Kortex auf Funktionsfähigkeit geprüft werden. Der Nachweis von solchen Funktionsdefiziten ist insbesondere in der Diagnostik neuropathischer Schmerzen relevant. ENG und SEP erfassen nur die dicken myelinisierten Afferenzen und die Hinterstrangbahnen. Somit fehlt diesen Verfahren die Sensitivität für Veränderungen der Funktion der dünnen nozizeptiven Afferenzen und des spinothalamischen Traktes (bei dissoziierter Sensibilitätsstörung). Diese Lücke wird durch Laser-evozierte Potenziale (LEP) geschlossen. LEP sind für die Funktionsprüfung peripherer und zentraler nozizeptiver Bahnen sensitiv und für zahlreiche neurologische Krankheitsbilder validiert; aufgrund hoher Gerätekosten steht das Verfahren noch nicht überall zur Verfügung.
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Treede, RD. (2014). Elektrophysiologische Messverfahren in der Schmerzmedizin . In: Baron, R., Koppert, W., Strumpf, M., Willweber-Strumpf, A. (eds) Praktische Schmerzmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54670-9_10-1
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DOI: https://doi.org/10.1007/978-3-642-54670-9_10-1
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