Zusammenfassung
Die Demenz ist eine Krankheit des höheren Lebensalters und hat sich durch den steigenden Anteil der älteren Bevölkerung in vielen Industrieländern zu einem großen Gesundheitsproblem entwickelt. Auch in den Entwicklungsländern ist in den nächsten Dekaden ein Zuwachs an Demenzpatienten zu erwarten. Häufigste Ursache ist die Alzheimersche Krankheit. Die Prävalenz nimmt ab dem 60. Lebensjahr rasch zu und erreicht bei 85jährigen 24–33% der Bevölkerung (Übersicht bei Ballard et al. 2011). Etwa 70% des Krankheitsrisikos ist genetisch bedingt. Bei 10% der Demenzkranken liegen potentiell reversible Grundkrankheiten vor, die sich nach rechtzeitiger Diagnose und anschließend spezifischer Therapie teilweise oder vollständig rückbilden können.
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Schwabe, U. (2013). Antidementiva. In: Schwabe, U., Paffrath, D. (eds) Arzneiverordnungs-Report 2013. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-37124-0_10
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