Abstract
The heart is comprised of three-dimensional components whose size, shape, and spatial interrelationships constantly change in an organized rhythmic fashion. The field of congenital heart disease encompasses the result of a disruption of the normal, but complex, three-dimensional internal anatomy and functioning of the heart. The diagnosis and treatment of congenital heart defects demand a precise and profound understanding of this dynamic anatomy and are therefore heavily reliant on real-time imaging. The open-heart surgeon has the benefit of comprehension and interaction with the real 3D anatomy; however this is usually static during open-heart surgery. The interventionalist wishing to employ minimally invasive transcatheter techniques in the beating heart has to build a mental concept of the anatomy usually derived from 2D echocardiographic and fluoroscopic data displayed on a screen. In general, the surgeon’s understanding of the anatomy is more complete and intuitive than that of the interventionalist even though they may be performing similar procedures, e.g., closure of an ASD secundum. In an attempt to bridge that gap, high-quality 3D volumetric data acquisition systems such as 3D transthoracic and transesophageal echocardiography, 3D rotational angiography, CT, and MRI have been developed. However this volumetric data is typically displayed on 2D screens which restrict the image to a single plane of view, preclude interaction directly with the image, and hamper the perception of depth. The development of a simple, accurate, and accessible 3D display for these data is a challenge, especially when attempting to display true depth.
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1 Introduction
The heart is comprised of three-dimensional components whose size, shape, and spatial interrelationships constantly change in an organized rhythmic fashion. The field of congenital heart disease encompasses the result of a disruption of the normal, but complex, three-dimensional internal anatomy and functioning of the heart. The diagnosis and treatment of congenital heart defects demand a precise and profound understanding of this dynamic anatomy and are therefore heavily reliant on real-time imaging. The open-heart surgeon has the benefit of comprehension and interaction with the real 3D anatomy; however this is usually static during open-heart surgery. The interventionalist wishing to employ minimally invasive transcatheter techniques in the beating heart has to build a mental concept of the anatomy usually derived from 2D echocardiographic and fluoroscopic data displayed on a screen. In general, the surgeon’s understanding of the anatomy is more complete and intuitive than that of the interventionalist even though they may be performing similar procedures, e.g., closure of an ASD secundum. In an attempt to bridge that gap, high-quality 3D volumetric data acquisition systems such as 3D transthoracic and transesophageal echocardiography, 3D rotational angiography, CT, and MRI have been developed. However this volumetric data is typically displayed on 2D screens which restrict the image to a single plane of view, preclude interaction directly with the image, and hamper the perception of depth. The development of a simple, accurate, and accessible 3D display for these data is a challenge, especially when attempting to display true depth.
Depth perception defines our ability to see an object, comprehend its position in space, and interact precisely with that object. The object’s three dimensionality and distance are perceived owing to the capacity of the visual cortex to simultaneously combine multiple depth cues including binocular stereopsis, convergence, and accommodation. Each eye, since it has a different position in the head, views an object from a slightly different angle, and this disparity, stereopsis, is employed by the brain as one of the cues for depth perception. Stereoscopy is a method which mimics stereopsis by presenting each eye with two slightly different versions of an image which, when combined in the brain, produce an illusion of depth. It is an illusion since all the points of light in the stereoscopic image are focused in a singular focal plane, whereas in a real object, these points arise from multiple different planes, and true depth perception has infinite focal planes (Fig. 44.1).
Even the highest-quality stereoscopic image is confined to one focal plane, and therefore interactions such as placing a device in the image, or manipulating the image with the observer’s hand inside it, are not possible since the device or hand occupies multiple focal planes. In addition, the source of stereoscopic images is at a distance from the observer; however the overlapping of the images to create the 3D illusion occurs up close. When attempting to interact with the up close 3D image, the eyes converge to focus on the hand or tool and lose their focus on the distant source, and the image becomes blurred. This discrepancy between the convergence depth cue and the distant focus creates a conflict in the brain often resulting in nausea. Recent attempts at enhancing the “image-anatomy” interaction and the operator’s experience with stereoscopic displays include virtual reality (VR) and augmented reality (AR). Although these methodologies may provide a better understanding of the patient’s anatomy and spatial relationship to the operator, they lack true depth perception and cannot be used for accurate navigation within the image.
Holography, from the Greek for “whole” and “drawing,” is a methodology which creates an exact visual replication of an object in three physical dimensions including all the depth cues, focal planes, and specific coordinates. The holographic image occupies an actual space and can be likened to an object created by a 3D printer where the material used to print is light. A high-quality hologram should be indistinguishable from the true object it represents (Fig. 44.2).
Computer-generated holograms (CGH) of patients’ 3D data could be useful in the clinical setting by providing the physician with a 3D image which is a true and spatially accurate representation of the patient’s anatomy, having all the visual depth cues. Since each point of light in the generated hologram is a distinct physical entity in real 3D space, it represents a precise anatomical coordinate in the patient, and interaction with and within the holographic image will simulate such interaction with and within the patients’ particular anatomy. Initial attempts at creating holograms in real time in an actual clinical setting have been recently reported using the RealView 3D dynamic holographic display and interface system [RealView Imaging, Yokneam, Israel]. The system projects high-resolution 3D live holographic images “floating in mid-air” without the need for any human-mounted device, goggles, or a conventional 2D screen. The projected 3D images appear in free space, allowing the user limitless accessibility to the image affording direct and precise interaction with and within the dynamic image. Therefore, a true volumetric display based on current 3D acquisition modalities maintains the interventionalist’s advantage of a minimally invasive approach and provides “real” 3D dynamic anatomy similar or even better than that of the surgeon, since the surgeon sees static 3D surfaces, while the hologram can display the organ at different levels of transparency to the viewer and can be easily cropped and manipulated as required.
The following figures are examples of holographic images created using the RealView system and demonstrate some of the interactions that can be performed and 3D acquisition modalities that can be used to create holograms in the clinical setting. Please note that holograms cannot be fully appreciated on a 2D page, but need to be observed directly. [Videos of holograms shown here in the figures can be viewed at www.realviewimaging.com]
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Conflict of interest: EB and CR are stockholders and employees of RealView Imaging.
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Bruckheimer, E., Rotschild, C. (2019). Holography in Congenital Heart Disease: Diagnosis and Transcatheter Treatment. In: Butera, G., Chessa, M., Eicken, A., Thomson, J.D. (eds) Atlas of Cardiac Catheterization for Congenital Heart Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-72443-0_44
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