Abstract
The aim of the study was to explore the connection of urea rebound and the difference between spKt/V and eKt/V and also the possibility of utilizing UV-absorbance measurements to assess urea rebound. Ten patients of chronic three-times-a-week hemodialysis (HD) were studied. On-line UV-absorbance of spent dialysate was monitored. Single-pool Kt/V (spKt/V), equilibrated Kt/V (eKt/V) and the percentage difference between spKt/V and eKt/V (ΔKt/V) were calculated. Urea rebound was calculated based on urea concentration in blood (Rb) and UV-absorbance in spent dialysate (Ra). ΔKt/V and Rb were not statistically different. Also, Ra and Rb were not statistically different. In summary, the results show that it is possible to assess post-dialysis urea rebound in blood based on UV-absorbance in spent dialysate, which may offer the opportunity to estimate the true dialysis dose and a more personalized approach to the dialysis treatment.
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Tomson, R., Uhlin, F., Fridolin, I. (2015). Optical Urea Rebound Estimation during Dialysis. In: Mindedal, H., Persson, M. (eds) 16th Nordic-Baltic Conference on Biomedical Engineering. IFMBE Proceedings, vol 48. Springer, Cham. https://doi.org/10.1007/978-3-319-12967-9_30
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DOI: https://doi.org/10.1007/978-3-319-12967-9_30
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-12966-2
Online ISBN: 978-3-319-12967-9
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