Skip to main content
SpringerLink
Log in

Bioactive Compounds and Biological Activities of Roscoea purpurea Sm.

  • Living reference work entry
  • First Online:
Bioactive Compounds in the Storage Organs of Plants

Part of the book series: Reference Series in Phytochemistry ((RSP))

  • 11 Accesses

Abstract

Roscoea purpurea Sm. (Family: Zingiberaceae) is a medicinally important herb endemic to the Himalayan region distributed from Himachal Pradesh to Arunachal Pradesh in India. The tuberous rhizomes of the species are used in traditional formulations as a tonic for seminal debility and many other diseases. The rhizomes are used as an ingredient of a popular Ayurvedic polyherbal formulation “Chyawanprash.” The species has been reported as a rich source of various nutritive constituents, minerals, phenolics, terpenoids, and carotenoids. Scientific studies showed that the rhizomes possess various pharmacological properties such as immunomodulatory, hepatoprotective, antidiabetic, hypolipidemic, anticancer, antioxidant, antibacterial, and antifungal effects. This chapter mainly focused on the scientific progress of the species related to nutritional and phytochemical composition, and pharmacological activities, with its potential in the nutraceutical market. However, research on the validation of traditional uses through pharmacological activities and clinical studies on humans is insufficient to support the species for ingredients of the dietary health supplements.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

Similar content being viewed by others

Abbreviations

ABTS:

2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging assay

ALT:

Alanine transaminase

AST:

Aspartate transferase

BHT:

Butylated hydroxytoluene

cpDNA:

Chloroplast DNA

DPPH:

2,2 Diphenyl 1 picrylhydrazyl radical scavenging assay

ELSD:

Evaporative light scattering detector

GAE:

Gallic acid equivalent

GC/MS:

Gas chromatography–mass spectrometry

HCT-116:

Human colorectal carcinoma cell line

HDL:

High-density lipoprotein

IC50:

Half maximal inhibitory concentration

IHR:

Indian Himalayan Region

ISSR:

Inter-simple sequence repeats

LDL:

Low-density lipoprotein

MBC:

Minimum bactericidal concentration

MIC:

Minimum inhibitory concentration

MTT:

3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay

NGS:

Next-generation sequencing

NJ:

Neighbor joining

nrDNA:

Nuclear ribosomal DNA

QE:

Quercetin equivalents

RP-HPLC:

Reverse phase High-performance liquid chromatography

SRBC:

Sheep red blood cells

References

  1. Kress WJ, Prince LM, Williams KJ (2002) The phylogeny and a new classification of the gingers (Zingiberaceae): evidence from molecular data. Amer J Bot 89:1682–1696

    Article  CAS  Google Scholar 

  2. Chattopadhyay I, Biswas K, Bandyopadhyay U, Banerjee RK (2004) Turmeric and curcumin: Biological actions and medicinal applications. Curr Sci 87:44–53

    Google Scholar 

  3. Cowley J, Wilford R, Bream R, Lock M (2007) The genus Roscoea. Royal Botanic Gardens, Kew

    Google Scholar 

  4. Dhyani A, Bahuguna YM, Nautiyal BP, Chaturvedi P, Nautiyal MC (2021) Ecological features and traditional knowledge of Roscoea alpina Royle a medicinal plant in Himalaya. Indian J Tradit Knowl 20:167–173

    Google Scholar 

  5. Zhao JL, Zhong J, Fan YL, Xia YM, Li QJ (2017) A preliminary species-level phylogeny of the alpine ginger Roscoea: implications for speciation. J Syst Evol 55:215–224

    Article  Google Scholar 

  6. Wilford R (1999) Roscoeas for the rock garden. Quarter Bull Alpine Garden Soc 67:93–101

    Google Scholar 

  7. Li DB, Ou XK, Zhao JL, Li QJ (2020) An ecological barrier between the Himalayas and the Hengduan Mountains maintains the disjunct distribution of Roscoea. J Biogeogr 47:326–341

    Article  Google Scholar 

  8. Das VB (1994) Materia medica of tibetean medicine. Sai Satguru publication, Delhi, pp 130–131

    Google Scholar 

  9. Chinmay R, Kumari S, Dhar B, Mohanty RC, Dixit R, Padhi MM, Baby R (2011) Pharmacognostical and phytochemical studies of Roscoea procera (Kakoli) and Lilium Polyphyllum (Ksheerkakoli) in comparison with market samples. Pharm J 23:32–38

    Google Scholar 

  10. Balkrishna A, Srivastava A, Mishra RK, Patel SP, Vashistha RK, Singh A et al (2012) Astavarga plants-threatened medicinal herbs of the North-West Himalaya. Int J Med Arom Plants 2:661–676

    Google Scholar 

  11. Rawat S, Andola H, Giri L, Dhyani P, Jugran A, Bhatt ID, Rawal RS (2014) Assessment of nutritional and antioxidant potential of selected vitality strengthening Himalayan medicinal plants. Int J Food Prop 17:703–712

    Article  CAS  Google Scholar 

  12. Wu D, Larsen K (1994) Zingiberaceae. retrieved 2011-10-01. In: Wu, Raven & Hong onwards. Flora of China. Science Press/Missouri Botanical Garden, Beijing/St. Louis

    Google Scholar 

  13. Mao AA, Bhaumik M (2007) Roscoea ngainoi (Zingiberaceae) sp. nov. from Manipur, India. Nord J Bot 25:299–302

    Article  Google Scholar 

  14. Mohandass D, Zhao JL, Xia YM, Campbell MJ, Li QJ (2015) Increasing temperature causes flowering onset time changes of alpine ginger Roscoea in the Central Himalayas. J Asia Pac Biodivers 8:191–198

    Article  Google Scholar 

  15. Ngamriabsakul C, Newman MF, Cronk QCB (2000) Phylogeny and disjunction in Roscoea (Zingiberaceae). Edinb J Bot 57:39–61

    Article  Google Scholar 

  16. Zhao JL, Paudel BR, Yu XQ, Zhang J, Li QJ (2021) Speciation along the elevation gradient: divergence of Roscoea species within the south slope of the Himalayas. Mol Phylogenet Evol 164:107292

    Article  PubMed  Google Scholar 

  17. Cowley EJ (1982) A revision of Roscoea (Zingiberaceae). Kew Bull 36:747–777

    Article  Google Scholar 

  18. Cowley J, Baker W (1994) Roscoea purpurea ‘red gurkha’: Zingiberaceae. Kew Mag 11:104–109

    Google Scholar 

  19. Wu D, Larsen K (2011) “Roscoea”, retrieved 2011-10-01. In: Wu Z, Raven PH, Hong D (eds) (onwards), Flora of China. Science Press/Missouri Botanical Garden, Beijing/St. Louis

    Google Scholar 

  20. Paudel BR, Shrestha M, Dyer AG, Zhu XF, Abdusalam A, Li QJ (2015) Out of Africa: evidence of the obligate mutualism between long corolla tubed plant and long-tongued fly in the Himalayas. Ecol Evol 5:5240–5251

    Article  PubMed  PubMed Central  Google Scholar 

  21. Paudel BR, Burd M, Shrestha M, Dyer AG, Li QJ (2018) Reproductive isolation in alpine gingers: how do coexisting Roscoea (R. purpurea and R. tumjensis) conserve species integrity? Evolution 72:1840–1850

    Article  PubMed  Google Scholar 

  22. Singh G, Rawat GS (2011) Ethnomedicinal survey of Kedarnath wildlife sanctuary in Western Himalaya, India. Indian J Fundam Appl Life Sci 1:35–46

    Google Scholar 

  23. Kaur G, Gupta V, Kumar S, Singhal RG, Maithani M, Bansal P (2019) Compliance level of textual therapeutic usage of kakoli-containing formulations with ethnomedicinal survey and modern system of medicine. Imam J Appl Sci 4:62–68

    Google Scholar 

  24. Shah R (2006) Nature’s medicinal plants of Uttaranchal. Gyanodaya Prakashan, Nainital

    Google Scholar 

  25. Misra A, Srivastava S, Verma S, Rawat AKS (2015) Nutritional evaluation, antioxidant studies and quantification of poly phenolics, in Roscoea purpurea tubers. BMC Res Notes 8:1–7

    Article  CAS  Google Scholar 

  26. Rana JC, Sharma BD, Jha BJ, Kumar M (2004) Cultivation of Hedychium spicatum (Kapoor Kachari), Valeriana wallichii and Roscoea purpurea in hill regions of India. Indian For 130:1008–1018

    Google Scholar 

  27. Sahu MS, Verma A, Mali PY, Rangari VD (2012) Isolation and characterization of bioactive compound from Roscoea procera Rhizomes. Bio Med 111:544–547

    Google Scholar 

  28. Kumari P, Joshi GC, Tewari LM (2011) Diversity and status of ethno-medicinal plants of Almora district in Uttarakhand, India. Int J Biodiv Conserv 3:298–326

    Google Scholar 

  29. Sahu RA, Itankar PR, Mishra RR, Maliye AN (2016) Pharmacological evaluation of Roscea procera (Kakoli) and Lilium polyphyllum (Kshirkakoli) extracts for immunomodulatory activity. Int J Pharmacogn Phytochem Res 8:1788–1794

    Google Scholar 

  30. Govindrajan R, Vinaykumar M, Pushpangadan P (2005) Antioxidant approach to disease management and the role of ‘Rasayana’ herb of Ayurveda. J Ethanopharmacol 99:165–178

    Article  Google Scholar 

  31. Govindarajan R, Singh DP, Rawat AKS (2007) High-performance liquid chromatographic method for the quantification of phenolics in ‘Chyavanprash’ a potent Ayurvedic drug. J Pharm Biomed Anal 43:527–532

    Article  CAS  PubMed  Google Scholar 

  32. Rawat S, Acharya P, Bhutia PO, Pandey A, Kumar D, Joshi R, Bhatt ID (2023) Changes in nutritional, physicochemical, phytochemical composition and antioxidant potential of Mahonia nepalensis fruits during ripening. Int J Food Prop 26:1062–1078

    Article  CAS  Google Scholar 

  33. Bhutia PO, Kewlani P, Pandey A, Rawat S, Bhatt ID (2021) Physico-chemical properties and nutritional composition of fruits of the wild Himalayan strawberry (Fragaria nubicola Lindle.) in different ripening stages. J Berry Res 11:481–496

    Article  CAS  Google Scholar 

  34. Rawat S, Bhatt ID, Rawal RS, Nandi SK (2017) Geographical and environmental variation in chemical constituents and antioxidant properties in Roscoea procera wall. J Food Biochem 41:e12302

    Article  Google Scholar 

  35. Srivastava S, Misra A, Kumar D, Srivastava A, Sood A, Rawat AKS (2015) Reversed-phase high-performance liquid chromatography-ultraviolet photodiode array detector validated simultaneous quantification of six bioactive phenolic acids in Roscoea purpurea tubers and their In vitro cytotoxic potential against various cell lines. Pharmacogn Mag 11:S488

    Article  PubMed  PubMed Central  Google Scholar 

  36. Giri L, Belwal T, Bahukhandi A, Suyal R, Bhatt ID, Rawal RS, Nandi SK (2017) Oxidative DNA damage protective activity and antioxidant potential of Ashtvarga species growing in the Indian Himalayan Region. Ind Crop Prod 102:173–179

    Article  CAS  Google Scholar 

  37. Miyazaki S, Devkota HP, Joshi KR, Watanabe T, Yahara S (2014) Chemical constituents from the aerial parts and rhizomes of Roscoea purpurea. Japan J Pharmacogn 68:99–100

    Google Scholar 

  38. Kaur G, Gupta V, Singhal RG, Rawal RK, Bansal P (2020) Isolation of catechins from Roscoea purpurea. J Young Pharm 12:389–391

    Article  CAS  Google Scholar 

  39. Singamaneni V, Lone B, Singh J, Kumar P, Gairola S, Singh S, Gupta P (2021) Coronarin K and L: two novel labdane diterpenes from Roscoea purpurea: an ayurvedic crude drug. Front Chem 9:642073

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  40. Williams CA, Harborne JB (1977) The leaf flavonoids of the Zingiberales. Biochem Syst Ecol 5:221–229

    Article  CAS  Google Scholar 

  41. Kaur G, Gupta V, Bansal P, Kumar S, Rawal RK, Singhal RG (2020) Isolation of lupenone (18-Lupen-3-one) from Roscoea purpurea root extract. Bangladesh J Medl Sci 19:692–696

    Article  Google Scholar 

  42. Bag BG, Barai AC (2020) Self-assembly of naturally occurring stigmasterol in liquids yielding a fibrillar network and gel. RSC Adv 10:4755–4762

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  43. Raval SS, Mandavia MK, Sanghani JM, Mahatma MK, Golakiya BA (2015) Separation and identification of phytochemicals from Roscoea procera Wall.(Kakoli), an ingredient of Ashtavarga. Indian J Agric Biochem 28:143–149

    Article  CAS  Google Scholar 

  44. Rawat S, Jugran AK, Bahukhandi A, Bahuguna A, Bhatt ID, Rawal RS, Dhar U (2016) Anti-oxidant and anti-microbial properties of some ethno-therapeutically important medicinal plants of Indian Himalayan. Region 3 Biotech 6:1–12

    Google Scholar 

  45. Kaur G, Gupta V, Singhal RG, Joshi MD, Rawal RK, Singh R, Bans P (2020) Isolation of chemical marker from Roscoea purpurea: first report. Human J 2:1–11

    Google Scholar 

  46. Bathla R, Sethi S, Prakash O, Punetha H, Pant AK, Batra M, Kumar M (2016) Phytochemical analysis, antioxidant and hepatoprotective activity of Roscoea purpurea, a Zingiberaceous herb collected from Kumaun hills of Uttarakhand. Asian J Tradit Med 11:141–152

    Google Scholar 

  47. Sahu MS, Mali PY, Waikar SB, Rangari VD (2011) Evaluation of immunomodulatory potential of ethanolic extract of Roscoea procera rhizomes in mice. J Pharm Bioallied Sci 2:346

    Article  Google Scholar 

  48. Bairwa R, Basyal D, Srivastav B (2012) Study of antidiabetic and hypolipidemic activity of Roscoea purpurea (zingiberaceae). Int J Inst Pharma Life Sci 2:130–137

    Google Scholar 

  49. Jugran AK, Rawat S, Devkota HP, Bhatt ID, Rawal RS (2021) Diabetes and plant-derived natural products: from ethnopharmacological approaches to their potential for modern drug discovery and development. Phytother Res 35:223–245

    Article  PubMed  Google Scholar 

  50. Tewari VP, Tewari KC, Yadava BBL (1976) Study of Roscoea procera Wall. (Kakoli-Ksheerkakoli of Astavarga). Quart J Crude Drug Res 14:69–70

    Article  CAS  Google Scholar 

  51. Das A (2008) Agro-techniques of selected medicinal plants. National Medicinal Plants Board, New Delhi

    Google Scholar 

  52. Bhatt ID, Prasad K, Rawat S, Rawal RS (2008) Evaluation of antioxidant phytochemical diversity in Hedychium spicatum: a high value medicinal plant of Himalaya. Pharmacogy Mag 4:202–205

    Google Scholar 

  53. Rawat S, Jugran AK, Bhatt ID, Rawal RS (2018) Influence of the growth phenophases on the phenolic composition and anti-oxidant properties of Roscoea procera Wall. in western Himalaya. J Food Sci Technol 55:578–585

    Article  CAS  PubMed  Google Scholar 

  54. Bhatt ID, Dauthal P, Rawat S, Gaira KS, Jugran A, Rawal RS, Dhar U (2012) Characterization of essential oil composition, phenolic content, and antioxidant properties in wild and planted individuals of Valeriana jatamansi Jones. Sci Hortic 136:61–68

    Article  CAS  Google Scholar 

  55. Fischer AM, Gan S (2007) Nutrient remobilization during leaf senescence. Ann Rev Senescence Proc Plants 26:87–107

    Article  CAS  Google Scholar 

  56. Govaerts R (2009) World checklist of selected plant families. Royal Botanic Gardens, Landon

    Google Scholar 

  57. Chen ZY (1987) The taxonomic significance of chromosome numbers in Zingiberaceae. In: Shui H, Tanaka R, Chen R, et al, Proceeding of the Sino-Japanese symposium on plant chromosomes, Beijing, pp 107–114

    Google Scholar 

  58. Chen ZY (1989) Evolutionary pattern in cytology and pollen structure of Asia Zingiberaceae. In: Holm-Nielsen LB, Nielsen IC, Balslev H (eds) Tropical forest: botanical dynamics, speciation and diversity. Aarhus University Academic Press, Carnwall, pp 185–191

    Chapter  Google Scholar 

  59. Bhattacharyya R (1968) Systematic status of the family Zingiberaceae. Nucleus (Supplement Vol.): 39–41

    Google Scholar 

  60. Mahanty HK (1970) Cytological study of the Zingiberales with special reference to their taxonomy. Cytologia 35:13–49

    Article  Google Scholar 

  61. Mehra PN, Sachdeva SK (1971) IOPB chromosome reports XXXIII. Taxon 20:609–614

    Article  Google Scholar 

  62. Zhang D, Duan L, Zhou N (2014) Application of DNA barcoding in Roscoea (Zingiberaceae) and a primary discussion on taxonomic status of Roscoea cautleoides var. pubescens. Biochem Syst Ecol 52:14–19

    Article  Google Scholar 

  63. Rawat S, Jugran AK, Bhatt ID, Rawal RS, Nandi SK (2016) Genetic diversity analysis in natural populations of Roscoea procera Wall. from West Himalaya, India. Brazil J Bot 39:621–630

    Article  Google Scholar 

  64. Bag BG, Shankar Dash S, Roy A (2014) Study of antioxidant property of the rhizome extract of Roscoea purpurea Sm. (Kakoli) and its use in green synthesis of gold nanoparticles. Int J Res Chem Env 4:174–180

    Google Scholar 

  65. Basri AM, Taha H, Ahmad N (2017) A review on the pharmacological activities and phytochemicals of Alpinia officinarum (Galangal) extracts derived from bioassay-guided fractionation and isolation. Pharmacogn Rev 11:43–56

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  66. Paudel BR, Kessler A, Shrestha M, Zhao JL, Li QJ (2019) Geographic isolation, pollination syndromes, and pollinator generalization in Himalayan Roscoea spp. (Zingiberaceae). Ecosphere 10:e02943

    Article  Google Scholar 

  67. Wang B, Kumar V, Olson A, Ware D (2019) Reviving the transcriptome studies: an insight into the emergence of single-molecule transcriptome sequencing. Front Genet 10:384

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  68. Ma M, Meng H, Lei E, Wang T, Zhang W, Lu B (2022) De novo transcriptome assembly, gene annotation, and EST-SSR marker development of an important medicinal and edible crop, Amomum tsaoko (Zingiberaceae). BMC Plant Biol 22:467

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  69. Taheri S, Abdullah TL, Rafii MY, Harikrishna JA, Werbrouck SP, Teo CH et al (2019) De novo assembly of transcriptomes, mining, and development of novel EST-SSR markers in Curcuma alismatifolia (Zingiberaceae family) through Illumina sequencing. Sci Rep 9:3047

    Article  PubMed  PubMed Central  Google Scholar 

  70. Ye Y, Xu Y, Li D, Tan J, Liu J (2021) Characterization of EST-SSR markers in Curcuma kwangsiensis SK Lee & CF Liang based on RNA sequencing and its application for phylogenetic relationship analysis and core collection construction. Genet Resour Crop Evol 68:1503–1516

    Article  CAS  Google Scholar 

  71. Sabu KK, Shehenaz MD, Amrutha J (2018) Transcriptome mining for Est-Indels and development of EST-SSR markers in turmeric (Curcuma longa L.). Int J Agric Environ Biotech 11:487–491

    Google Scholar 

  72. Vidya V, Prasath D, Snigdha M, Gobu R, Sona C, Maiti CS (2021) Development of EST-SSR markers based on transcriptome and its validation in ginger (Zingiber officinale Rosc.). PLoS One 16:e0259146

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  73. Deng K, Deng R, Fan J, Chen E (2018) Transcriptome analysis and development of simple sequence repeat (SSR) markers in Zingiber striolatum Diels. Physiol Mol Biol Plants 24:125–134

    Article  CAS  PubMed  Google Scholar 

  74. Sharma H, Kumar P, Singh A, Aggarwal K, Roy J, Sharma V, Rawat S (2020) Development of polymorphic EST-SSR markers and their applicability in genetic diversity evaluation in Rhododendron arboreum. Mol Biol Rep 47:2447–2457

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgments

SR thanks the Director of GBPNIHE for providing facilities and encouragement. In-house Projects no-02 and 04 of the institute are greatly acknowledged for partial financial support in conducting the research work.

Author information

Authors and Affiliations

  1. G.B. Pant National Institute of Himalayan Environment, Sikkim Regional Centre, Gangtok, Sikkim, India

    Sandeep Rawat

  2. G.B. Pant National Institute of Himalayan Environment, Garhwal Regional Centre, Srinagar, Uttarakhand, India

    Arun Jugran

Authors
  1. Sandeep Rawat
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Arun Jugran
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Sandeep Rawat .

Editor information

Editors and Affiliations

  1. Department of Botany, Karnatak University, Dharwad, Karnataka, India

    Hosakatte Niranjana Murthy

  2. Research Center for the Development of Advanced Horticultural Technology, Chungbuk National University, Cheongju, Korea (Republic of)

    Kee Yoeup Paek

  3. Dept of Horticultural Science, Chungbuk National University, Cheongju, Korea (Republic of)

    So-Young Park

Rights and permissions

Reprints and permissions

Copyright information

© 2023 Springer Nature Switzerland AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Rawat, S., Jugran, A. (2023). Bioactive Compounds and Biological Activities of Roscoea purpurea Sm.. In: Murthy, H.N., Paek, K.Y., Park, SY. (eds) Bioactive Compounds in the Storage Organs of Plants. Reference Series in Phytochemistry. Springer, Cham. https://doi.org/10.1007/978-3-031-29006-0_31-1

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-29006-0_31-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-29006-0

  • Online ISBN: 978-3-031-29006-0

  • eBook Packages: Springer Reference Chemistry and Mat. ScienceReference Module Physical and Materials ScienceReference Module Chemistry, Materials and Physics

Publish with us

Policies and ethics

Search

Navigation