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DNA Methylation Analysis in Human Cancer

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Pancreatic Cancer

Part of the book series: Methods in Molecular Biology ((MIMB,volume 980))

Abstract

The functional impact of aberrant DNA methylation and the widespread alterations in DNA methylation in cancer development have led to the development of a variety of methods to characterize the DNA methylation patterns. This chapter critiques and describes the major approaches to analyzing DNA methylation.

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Acknowledgments

This work was supported by NIH grants (CA62924, R01CA120432, RC2CA148376, and the Michael Rolfe Foundation).

Disclosures: None of the authors have any relevant potential conflicts.

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Authors and Affiliations

  1. Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA

    Eileen O’Sullivan & Michael Goggins

  2. Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD, USA

    Michael Goggins

  3. Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, MD, USA

    Michael Goggins

Authors
  1. Eileen O’Sullivan
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  2. Michael Goggins
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Corresponding author

Correspondence to Michael Goggins .

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Editors and Affiliations

  1. , Irving Cancer Research Center, Columbia University, St. Nicholas Avenue 1130, New York, 10032, New York, USA

    Gloria H. Su

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O’Sullivan, E., Goggins, M. (2013). DNA Methylation Analysis in Human Cancer. In: Su, G. (eds) Pancreatic Cancer. Methods in Molecular Biology, vol 980. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-287-2_7

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  • DOI: https://doi.org/10.1007/978-1-62703-287-2_7

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-286-5

  • Online ISBN: 978-1-62703-287-2

  • eBook Packages: Springer Protocols

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