Skip to main content

Osteopenia and Osteoporosis

Family Medicine
  • 1482 Accesses

Abstract

Osteoporosis is a major health concern worldwide and within the United States. Approximately 9 % of U.S. adults over the age of 50 have osteoporosis, and up to 50 % have some degree of low bone density [1]. Osteoporosis causes more than two million fractures per year with $19 billion in associated costs in the United States alone [2]. The clinical costs of an osteoporotic fracture are equally great and include increased mortality, increased disability, and an increased need for long-term nursing care. The most common sites of fracture are the hip, vertebrae, and wrist. Hip fractures are particularly deadly, carrying a 26 % 1-year mortality rate for patients over the age of 69. Of those who survive, functional skills are significantly decreased with decreased fine motor and mobility scores [3]. Vertebral fractures lead to chronic back pain and deformity in up to 30 % of patients. These fractures may have a long-term impact on overall quality of life and the ability to carry out activities of daily living (ADL).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

Similar content being viewed by others

References

  1. Looker AC, Borrud LG, Dawson-Hughes B, Shepherd JA, Wright NC. Osteoporosis or low bone mass at the femur neck or lumbar spine in older adults: United States, 2005–2008. NCHS Data Brief. 2012; 93:1–8.

    Google Scholar 

  2. National Osteoporosis Foundation. What is osteoporosis? http://www.nof.org/osteoporosis/articles/7. Accessed 19 Feb 2014.

  3. Bentler SE, Liu L, Obrizan M, Cook EA, Wright KB, Geweke JF, Chrischilles EA, Pavlik CE, Wallace RB, Ohsfeldt RL, Jones MP, Rosenthal GE, Wolinsky FD. The aftermath of hip fracture: discharge placement, functional status change, and mortality. Am J Epidemiol. 2009;170(10):1290.

    Article  PubMed Central  PubMed  Google Scholar 

  4. Hiligsmann M, Bruyère O, Ethgen O, Gathon HJ, Reginster JY. Lifetime absolute risk of hip and other osteoporotic fracture in Belgian women. Bone. 2008;43(6):991–4.

    Article  PubMed  Google Scholar 

  5. Diab DL, Watts NB. Secondary osteoporosis: differential diagnosis and workup. Clin Obstet Gynecol. 2002;288(18):2300.

    Google Scholar 

  6. The NIH Osteoporosis and Related Bone Diseases~National Resource Center. Smoking and bone health. http://www.niams.nih.gov/Health_Info/Bone/Osteoporosis/Conditions_Behaviors/bone_smoking.asp. Accessed 19 Feb 2015.

  7. Wang PS, Solomon DH, Mogun H, Avorn J. HMG-CoA reductase inhibitors and the risk of hip fractures in elderly patients. JAMA. 2000;283:3211.

    Article  CAS  PubMed  Google Scholar 

  8. Feskanich D, Willett W, Colditz G. Walking and leisure-time activity and risk of hip fracture in postmenopausal women. JAMA. 2002;288(18):2300.

    Article  PubMed  Google Scholar 

  9. Diab DL, Watts NB. Secondary osteoporosis: differential diagnosis and workup. Clin Obstet Gynecol. 2013;56(4):686–93.

    Article  PubMed  Google Scholar 

  10. The International Society for Densitometry. 2013 ISCD official positions – adult. Middletown: The International Society for Densitometry. http://www.iscd.org/official-positions/2013-iscd-official-positions-adult/. Accessed 3 Jan 2015.

  11. Kanis JA, on behalf of the World Health Organization Scientific Group. Assessment of osteoporosis at the primary health-care level. Technical report. World Health Organization Collaborating Centre for Metabolic Bone Diseases, University of Sheffield. http://www.shef.ac.uk/FRAX/pdfs/WHO_Technical_Report.pdf. Accessed 22 Dec 2014.

  12. WHO Fracture Risk Assessment Tool (FRAX). http://www.shef.ac.uk/FRAX. Accessed 23 Dec 2014.

  13. New recommended daily amounts of Calcium and Vitamin D. NIH Medline Plus. Winter 2011; 5(4): 12. http://www.nlm.nih.gov/medlineplus/magazine/issues/winter11/articles/winter11pg12.html. Accessed 19 Feb 2015.

  14. Jackson RD, LaCroix AZ, Gass M, Wallace RB, Robbins J, Lewis CE, et al. Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med. 2006;354(7):669.

    Article  CAS  PubMed  Google Scholar 

  15. National Osteoporosis Foundation. Calcium and Vitamin D: what you need to know. http://nof.org/articles/10#howmuchvitamind. Accessed 23 Dec 2014.

  16. Howe TE, Shea B, Dawson LJ, Downie F, Murray A, Ross C, et al. Exercise for preventing and treating osteoporosis in postmenopausal women. Cochrane Database Syst Rev. 2011; 7(CD000333).

    Google Scholar 

  17. Rossouw JE, Anderson GL, Prentice RL, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principle results from the Women’s Health Initiative randomized controlled trial. JAMA. 2002;288(3):321–33.

    Article  CAS  PubMed  Google Scholar 

  18. Eng-Wong J, Reynolds JC, Venzon D, Liewehr D, Gantz S, Danforth D, et al. Effect of raloxifene on bone mineral density in premenopausal women at increased risk of breast cancer. J Clin Endocrinol Metab. 2006;91(10):3941.

    Article  CAS  PubMed  Google Scholar 

  19. Knopp-Sihota JA, Newburn-Cook CV, Homik J, Cummings GG, Voaklander D. 1- Calcitonin for treating acute and chronic pain of recent and remote osteoporotic vertebral compression fractures: a systematic review and meta-analysis. Osteoporos Int. 2012;23(1):17.

    Article  CAS  PubMed  Google Scholar 

  20. Downs Jr RW, Bell NH, Ettinger MP, Walsh BW, Favus MJ, Mako B, Wang L, Smith ME, Gormley GJ, Melton ME. Comparison of alendronate and intranasal calcitonin for treatment of osteoporosis in postmenopausal women. J Clin Endocrinol Metab. 2000;85(5):1783.

    CAS  PubMed  Google Scholar 

  21. Vahle JL, Sato M, Long GG, et al. Skeletal changes in rats given daily subcutaneous injections of recombinant human parathyroid hormone (1–34) for 2 years and relevance to human safety. Toxicol Pathol. 2002;30(3):312.

    Article  CAS  PubMed  Google Scholar 

  22. Cummings SR, San Martin J, McClung MR, et al. Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N Engl J Med. 2009;361(8):756–65.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Katherine Reeve .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer International Publishing Switzerland (outside the USA)

About this entry

Cite this entry

Reeve, K., West, R. (2015). Osteopenia and Osteoporosis. In: Paulman, P., Taylor, R. (eds) Family Medicine. Springer, Cham. https://doi.org/10.1007/978-1-4939-0779-3_129-1

Download citation

  • DOI: https://doi.org/10.1007/978-1-4939-0779-3_129-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Online ISBN: 978-1-4939-0779-3

  • eBook Packages: Springer Reference MedicineReference Module Medicine

Publish with us

Policies and ethics

Chapter history

  1. Latest

    Osteopenia and Osteoporosis
    Published:
    12 December 2020

    DOI: https://doi.org/10.1007/978-1-4939-0779-3_129-2

  2. Original

    Osteopenia and Osteoporosis
    Published:
    28 September 2015

    DOI: https://doi.org/10.1007/978-1-4939-0779-3_129-1