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DNA Vaccines in Pigs: From Immunization to Antigen Identification

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Vaccine Technologies for Veterinary Viral Diseases

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2465))

Abstract

DNA vaccination is one of the most fascinating vaccine strategies currently in development. Two of the main advantages of DNA immunization rely on its simplicity and flexibility, being ideal to dissect both the immune mechanisms and the antigens involved in protection against a given pathogen. Here we describe several strategies used to enhance the immune responses induced and the protection afforded by experimental DNA vaccines tested in swine and provide very basic protocols describing the generation and in vivo application of a prototypic DNA vaccine. The future will say the last word regarding the definitive implementation of DNA vaccination in the field.

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Acknowledgments

This work was supported by the Spanish Government (Project reference numbers: PID2019-107616RB-I00 and AGL2016-78160-C2-1-R).

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Authors and Affiliations

  1. IRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA), Bellaterra, Barcelona, Spain

    Francesc Accensi, Laia Bosch-Camós, Paula L. Monteagudo & Fernando Rodríguez

  2. Departament de Sanitat i d’Anatomia Animals, Universitat Autònoma de Barcelona (UAB), Bellaterra, Barcelona, Spain

    Francesc Accensi

Authors
  1. Francesc Accensi
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  2. Laia Bosch-Camós
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  3. Paula L. Monteagudo
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  4. Fernando Rodríguez
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Corresponding author

Correspondence to Francesc Accensi .

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Editors and Affiliations

  1. Centro de Investigación en Sanidad Animal (CISA), INIA-CSIC, Valdeolmos, Madrid, Spain

    Alejandro Brun

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Accensi, F., Bosch-Camós, L., Monteagudo, P.L., Rodríguez, F. (2022). DNA Vaccines in Pigs: From Immunization to Antigen Identification. In: Brun, A. (eds) Vaccine Technologies for Veterinary Viral Diseases. Methods in Molecular Biology, vol 2465. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2168-4_6

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  • DOI: https://doi.org/10.1007/978-1-0716-2168-4_6

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-2167-7

  • Online ISBN: 978-1-0716-2168-4

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