Abstract
Lymphedema is a chronic, untreatable, progressive disease resulting from a transport disorder in the lymphatic drainage system, with consecutive proliferation and alteration of tissue fluid, as well as alteration of tissue of the affected body part. Lymphedema can affect all areas of the body surface, but also the internal organs – especially in lymphedema-associated syndromes. Lymphedema is classified according to four clinical stages, the age of manifestation (congenital, lymphedema praecox, lymphedema tardum), and etiopathogenesis (primary, secondary). In recent years, several genes have been identified, the mutations of which are associated with primary lymphedema. There is currently no causal treatment for lymphedema, so the treatment is purely symptomatic.
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References
Connell FC, Gordon K, Brice G et al (2013) The classification and diagnostic algorithm for primary lymphatic dysplasia: an update from 2010 to include molecular findings. Clin Genet 84:303–314
First Describer
Jester HG (1977) Lymphedema distichiasis. A rare hereditary syndrome. Hum Genet 39:113–116
Kinmonth JB, Taylor GW (1964) Chylous reflux. BMJ 1:529–532
Meige HC (1889) Le trophoedème chronique héréditaire. Nouv Iconogr Salpêt Paris 12:453–480
Meige H (1898) Dystrophie oedemateuse hereditaire presse Med 6:341–343
Milroy WF (1892) An undescribed variety of hereditary oedema. N Y Med J 56:505–508
Nonne M (1891) Vier Fälle von Elephantiasis congenita hereditaria. Virchows Arch Pathol Anat (Berlin) 125:189–196
Secrétan H (1901) Odeme dur et hyperplasie traumatique du métacarpe dorsal. Rev Med Suisse Novel 21:409–416
Stemmer R (1976) Ein klinisches Zeichen zur Früh- und Differenzialdiagnose des Lymphödems. Vasa 5:261–262
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Gaber, Y. (2022). Diseases of Lymphatics. In: Plewig, G., French, L., Ruzicka, T., Kaufmann, R., Hertl, M. (eds) Braun-Falco´s Dermatology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-63709-8_67
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DOI: https://doi.org/10.1007/978-3-662-63709-8_67
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