Definition

A member of one of the two major chemical classes of local anesthetics, differentiated by the intermediate chain linking a lipophilic group and an ionizable group (usually a tertiary amine). The pharmacologic class of agents comprised of lidocaine, bupivacaine, ropivacaine, mepivacaine, prilocaine and etidocaine.

The other major class is ester anesthetic.

Acute Pain in Children, Post-Operative

Drugs with Mixed Action and Combinations, Emphasis on Tramadol

Postoperative Pain, Methadone