Generic Name

Atomoxetine

Brand Name

Strattera

Class

ADHD agents

Proposed Mechanism(s) of Action

Inhibits the presynaptic reuptake of norepinephrine and theoretically increases dopamine in the prefrontal cortex via the same mechanism.

Indication

Attention deficit/hyperactivity disorder.

Off-Label Use

Treatment-resistant depression and anxiety.

Side Effects

Serious

Increased cardiac rate, potential hypertension, orthostatic hypotension, rare liver damage, potential for induction of mania, and suicidal ideation.

Common

Sedation in children, decreased appetite, dry mouth, constipation, nausea, vomiting, dysmenorrhea, erectile dysfunction, and impaired libido.