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Stratum Corneum Desquamation

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Agache’s Measuring the Skin

Abstract

Desquamation is a regular process participating in the stratum corneum self-renewal. It is globally correlated with the intercorneocyte cohesion and binding forces. Scaliness and xerosis represent frequent disorders of desquamation. The methods of assessment rely either on spontaneous or forced desquamation. Presently, the most common procedures involve specially designed tapes and cyanoacrylate skin surface strippings. The corneocytes are possibly stained in vivo using fluorescent or chromatic dyes. Assessments rely on visual, gravimetric, photometric, specular light reflectance, and image analysis methods.

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Abbreviations

ACD:

Adhesive-coated disk

CSSS:

Cyanoacrylate skin surface stripping

DC:

Dansyl chloride

DHA:

Dihydroxyacetone

ETT:

Epidermal turnover time

NMF:

Natural moisturizing factor

SC:

Stratum corneum

SCMI:

Skin capacitance mapping/imaging

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Correspondence to Gérald E. Piérard .

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Piérard, G.E., Hermanns-Lê, T., Piérard-Franchimont, C. (2015). Stratum Corneum Desquamation. In: Humbert, P., Maibach, H., Fanian, F., Agache, P. (eds) Agache’s Measuring the Skin. Springer, Cham. https://doi.org/10.1007/978-3-319-26594-0_25-1

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  • DOI: https://doi.org/10.1007/978-3-319-26594-0_25-1

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