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Nicotine Dependence and Recommendations for Smoking Cessation

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Airway Diseases

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Abstract

Tobacco use and dependence is one of the leading causes of preventable mortality and morbidity in the world. Intervention for smoking cessation has become an urgent need because of increasing tobacco use and health hazards, especially in developing countries. The chapter highlights the non-pharmacological and pharmacological treatment strategies of tobacco dependence. In addition, treatment strategies in target groups such as pregnancy, adolescence, respiratory diseases, cardiovascular diseases, etc. are summarized.

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References

  1. Hays JT, Ebbert JO. Adverse effects and tolerability of medications for the treatment of tobacco use and dependence. Drugs. 2010;70(18):2357–72. https://doi.org/10.2165/11538190-000000000-00000.

    Article  CAS  Google Scholar 

  2. Giulietti F, Filipponi A, Rosettani G, et al. Pharmacological approach to smoking cessation: an updated review for daily clinical practice [published online ahead of print, 2020 Jun 23]. High Blood Press Cardiovasc Prev. 2020:1–14. https://doi.org/10.1007/s40292-020-00396-9.

  3. Nagano T, Katsurada M, Yasuda Y, Kobayashi K, Nishimura Y. Current pharmacologic treatments for smoking cessation and new agents undergoing clinical trials. Ther Adv Respir Dis. 2019;13:1753466619875925. https://doi.org/10.1177/1753466619875925.

    Article  Google Scholar 

  4. Widysanto A, Combest FE, Dhakal A, Saadabadi A. Nicotine addiction. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2020.

    Google Scholar 

  5. Sales MPU, Araújo AJ, Chatkin JM, et al. Update on the approach to smoking in patients with respiratory diseases. J Bras Pneumol. 2019;45(3):e20180314. https://doi.org/10.1590/1806-3713/e20180314.

    Article  Google Scholar 

  6. Prochaska JO, DiClemente CC. Transtheoretical therapy: toward a more integrative model of change. Psychother Theory Res Pract Train. 1982;19(3):276–88. https://doi.org/10.1037/h0088437.

    Article  Google Scholar 

  7. World Health Organization. Toolkit for delivering the 5A’s and 5R’s brief tobacco interventions in primary care. 2014. https://www.who.int/tobacco/publications/smoking_cessation/9789241506953/en/. Accessed 5 June 2020.

  8. Zwar NA. Smoking cessation. Aust J Gen Pract. 2020;49(8):474–81. https://doi.org/10.31128/AJGP-03-20-5287.

    Article  Google Scholar 

  9. Pacek LR, McClernon FJ, Bosworth HB. Adherence to pharmacological smoking cessation interventions: a literature review and synthesis of correlates and barriers. Nicotine Tob Res. 2018;20(10):1163–72. https://doi.org/10.1093/ntr/ntx210.

    Article  Google Scholar 

  10. Ashe ML, Wilson SJ. Very light daily smoking in young adults: relationships between nicotine dependence and lapse. Nicotine Tob Res. 2020;ntaa169 https://doi.org/10.1093/ntr/ntaa169.

  11. Fagerström KO, Heatherton TF, Kozlowski LT. Nicotine addiction and its assessment. Ear Nose Throat J. 1990;69(11):763–5.

    Google Scholar 

  12. Fagerström K. Determinants of tobacco use and renaming the FTND to the Fagerström test for cigarette dependence. Nicotine Tob Res. 2012;14:75–8. https://doi.org/10.1093/ntr/ntr137.

    Article  Google Scholar 

  13. Heatherton TF, Kozlowski LT, Frecker RC, Rickert W, Robinson J. Measuring the heaviness of smoking: using self-reported time to the first cigarette of the day and number of cigarettes smoked per day. Br J Addict. 1989;84(7):791–9.

    Article  CAS  Google Scholar 

  14. García-Gómez L, Hernández-Pérez A, Noé-Díaz V, Riesco-Miranda JA, Jiménez-Ruiz C. Smoking cessation treatments: current psychological and pharmacological options. Rev Investig Clin. 2019;71(1):7–16. https://doi.org/10.24875/RIC.18002629.

    Article  Google Scholar 

  15. Hartmann-Boyce J, Hong B, Livingstone-Banks J, Wheat H, Fanshawe TR. Additional behavioural support as an adjunct to pharmacotherapy for smoking cessation. Cochrane Database Syst Rev. 2019;6(6):CD009670. https://doi.org/10.1002/14651858.CD009670.pub4.

  16. Lancaster T, Stead LF. Individual behavioural counselling for smoking cessation. Cochrane Database Syst Rev. 2017;(3) https://doi.org/10.1002/14651858.CD001292.pub3.

  17. Valera P, Acuna N, Vento I. The preliminary efficacy and feasibility of group-based smoking cessation treatment program for incarcerated smokers. Am J Mens Health. 2020;14(4):1557988320943357. https://doi.org/10.1177/1557988320943357.

    Article  Google Scholar 

  18. Stead LF, Carroll AJ, Lancaster T. Group behavior therapy programmes for smoking cessation. Cochrane Database Syst Rev. 2017(3). https://doi.org/10.1002/14651858.CD001007.pub3.

  19. Wu L, He Y, Jiang B, Zhang D, Tian H, Zuo F, Lam TH. Very brief physician advice and supplemental proactive telephone calls to promote smoking reduction and cessation in Chinese male smokers with no intention to quit: a randomized trial. Addiction. 2017;112(11):2032–40. https://doi.org/10.1111/add.13908.

    Article  Google Scholar 

  20. Scheffers-van Schayck T, Otten R, Engels RCME, Kleinjan M. Proactive telephone smoking cessation counseling tailored to parents: results of a randomized controlled effectiveness trial. Int J Environ Res Public Health. 2019;16(15):2730. https://doi.org/10.3390/ijerph16152730.

    Article  Google Scholar 

  21. Matkin W, Ordóñez-Mena JM, Hartmann-Boyce J. Telephone counselling for smoking cessation. Cochrane Database Syst Rev. 2019;5(5):CD002850. Published 2019 May 2. https://doi.org/10.1002/14651858.CD002850.pub4.

    Article  Google Scholar 

  22. Haskins BL, Lesperance D, Gibbons P, Boudreaux ED. A systematic review of smartphone applications for smoking cessation. Transl Behav Med. 2017;7(2):292–9. https://doi.org/10.1007/s13142-017-0492-2. [Medline:28527027]

    Article  Google Scholar 

  23. Lüscher J, Berli C, Schwaninger P, Scholz U. Smoking cessation with smartphone applications (SWAPP): study protocol for a randomized controlled trial. BMC Public Health. 2019;19(1):1400. https://doi.org/10.1186/s12889-019-7723-z.

    Article  Google Scholar 

  24. Kato A, Tanigawa T, Satake K, Nomura A. Efficacy of the ascure smoking cessation program: retrospective study. JMIR Mhealth Uhealth. 2020;8(5):e17270. https://doi.org/10.2196/17270.

    Article  Google Scholar 

  25. Bricker JB, Watson NL, Mull KE, Sullivan BM, Heffner JL. Efficacy of smartphone applications for smoking cessation: a randomized clinical trial. JAMA Intern Med. 2020;180(11):1–9. https://doi.org/10.1001/jamainternmed.2020.4055. Epub ahead of print.

    Article  Google Scholar 

  26. Webb J, Peerbux S, Smittenaar P, et al. Preliminary outcomes of a digital therapeutic intervention for smoking cessation in adult smokers: randomized controlled trial. JMIR Ment Health. 2020;7(10):e22833. https://doi.org/10.2196/22833.

    Article  Google Scholar 

  27. Taylor GMJ, Dalili MN, Semwal M, Civljak M, Sheikh A, Car J. Internet-based interventions for smoking cessation. Cochrane Database Syst Rev. 2017;9(9):CD007078. https://doi.org/10.1002/14651858.CD007078.pub5.

    Article  Google Scholar 

  28. Graham AL, Carpenter KM, Cha S, Cole S, Jacobs MA, Raskob M, Cole-Lewis H. Systematic review and meta-analysis of internet interventions for smoking cessation among adults. Subst Abus Rehabil. 2016;7:55–69. https://doi.org/10.2147/SAR.S101660.

    Article  Google Scholar 

  29. Livingstone-Banks J, Ordóñez-Mena JM, Hartmann-Boyce J. Print-based self-help interventions for smoking cessation. Cochrane Database Syst Rev. 2019;1(1):CD001118. https://doi.org/10.1002/14651858.CD001118.pub4.

    Article  Google Scholar 

  30. Byaruhanga J, Atorkey P, McLaughlin M, et al. Effectiveness of individual real-time video counseling on smoking, nutrition, alcohol, physical activity, and obesity health risks: systematic review. J Med Internet Res. 2020;22(9):e18621. https://doi.org/10.2196/18621.

    Article  Google Scholar 

  31. Hong Z, Li N, Li D, et al. Telemedicine during the COVID-19 pandemic: experiences from Western China. J Med Internet Res. 2020;22(5):e19577. https://doi.org/10.2196/19577.

    Article  Google Scholar 

  32. Byaruhanga J, Wiggers J, Paul CL, Byrnes E, Mitchell A, Lecathelinais C, Tzelepis F. Acceptability of real-time video counselling compared to other behavioural interventions for smoking cessation in rural and remote areas. Drug Alcohol Depend. 2020;217:108296. https://doi.org/10.1016/j.drugalcdep.2020.108296.

    Article  Google Scholar 

  33. Fanshawe TR, Hartmann-Boyce J, Perera R, Lindson N. Competitions for smoking cessation. Cochrane Database Syst Rev. 2019;2(2):CD013272. https://doi.org/10.1002/14651858.CD013272.

    Article  Google Scholar 

  34. Evoy KE, Ford KH, Nduaguba S, Taylor A, Thomas L. A pilot study assessing the addition of a Quit and Win program to pharmacist-led intensive smoking cessation therapy in a predominantly underserved, minority population. Tob Prev Cessat. 2019;5:44. https://doi.org/10.18332/tpc/113356.

    Article  Google Scholar 

  35. Leone FT, Zhang Y, Evers-Casey S, et al. Initiating pharmacologic treatment in tobacco-dependent adults. An official American Thoracic Society clinical practice guideline. Am J Respir Crit Care Med. 2020;202(2):e5–e31. https://doi.org/10.1164/rccm.202005-1982ST.

    Article  Google Scholar 

  36. Melka AS, Chojenta CL, Holliday EG, Loxton DJ. Effectiveness of pharmacotherapy for smoking cessation: protocol for umbrella review and quality assessment of systematic reviews. Syst Rev. 2018;7(1):210. https://doi.org/10.1186/s13643-018-0878-3.

    Article  Google Scholar 

  37. Gonzales D, Rennard SI, Nides M, et al., Varenicline Phase 3 Study Group. Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: a randomized controlled trial. JAMA. 2006;296(1):47–55. https://doi.org/10.1001/jama.296.1.47.

  38. Tønnesen P, Mikkelsen KL. Smoking cessation with four nicotine replacement regimes in a lung clinic. Eur Respir J. 2000;16(4):717–22. https://doi.org/10.1034/j.1399-3003.2000.16d25.x.

    Article  Google Scholar 

  39. Jorenby DE, Leischow SJ, Nides MA, et al. A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation. N Engl J Med. 1999;340(9):685–91. https://doi.org/10.1056/NEJM199903043400903.

    Article  CAS  Google Scholar 

  40. Lindson N, Chepkin SC, Ye W, Fanshawe TR, Bullen C, Hartmann-Boyce J. Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation. Cochrane Database Syst Rev. 2019;4(4):CD013308. https://doi.org/10.1002/14651858.CD013308.

    Article  Google Scholar 

  41. Anthenelli RM, Benowitz NL, West R, et al. Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial. Lancet. 2016;387(10037):2507–20. https://doi.org/10.1016/S0140-6736(16)30272-0.

    Article  CAS  Google Scholar 

  42. Hays JT, Hurt RD, Rigotti NA, et al. Sustained-release bupropion for pharmacologic relapse prevention after smoking cessation. A randomized, controlled trial. https://doi.org/10.7326/0003-4819-135-6-200109180-00011.

  43. Hays JT, Ebbert JO. Bupropion sustained release for treatment of tobacco dependence. Mayo Clin Proc. 2003;78(8):1020–4; quiz 1024. https://doi.org/10.4065/78.8.1020.

    Article  CAS  Google Scholar 

  44. Jiménez Ruiz CA, Ramos Pinedo A, Cicero Guerrero A, Mayayo Ulibarri M, Cristobal Fernández M, Lopez Gonzalez G. Characteristics of COPD smokers and effectiveness and safety of smoking cessation medications. Nicotine Tob Res. 2012;14(9):1035–9. https://doi.org/10.1093/ntr/nts001. Epub 2012 Feb 17.

    Article  CAS  Google Scholar 

  45. Gobarani RK, Abramson MJ, Bonevski B, et al. The efficacy and safety of varenicline alone versus in combination with nicotine lozenges for smoking cessation among hospitalised smokers (VANISH): study protocol for a randomised, placebo-controlled trial. BMJ Open. 2020;10(10):e038184. https://doi.org/10.1136/bmjopen-2020-038184.

    Article  Google Scholar 

  46. Zhong Z, Zhao S, Zhao Y, Xia S. Combination therapy of varenicline and bupropion in smoking cessation: a meta-analysis of the randomized controlled trials. Compr Psychiatry. 2019;95:152125. https://doi.org/10.1016/j.comppsych.2019.152125. Epub 2019 Sept 5.

    Article  Google Scholar 

  47. Rose JE, Behm FM. Combination varenicline/bupropion treatment benefits highly dependent smokers in an adaptive smoking cessation paradigm. Nicotine Tob Res. 2017;19(8):999–1002. https://doi.org/10.1093/ntr/ntw283.

    Article  CAS  Google Scholar 

  48. Salepci B. Other pharmacological and developing treatments in smoking cessation/nicotine vaccines (Sigara Bırakmada Diğer Farmakolojik Tedaviler ve Gelişmekte Olanlar/ Nikotin Aşısı). Güncel Göğüs Hastalıkları Serisi. 2016;4(1):118–27. https://doi.org/10.5152/gghs.2016.017.

    Article  Google Scholar 

  49. Howes S, Hartmann-Boyce J, Livingstone-Banks J, Hong B, Lindson N. Antidepressants for smoking cessation. Cochrane Database Syst Rev. 2020;4(4):CD000031. https://doi.org/10.1002/14651858.CD000031.pub5.

    Article  Google Scholar 

  50. LiverTox. Clinical and research information on drug-induced liver injury [Internet]. Bethesda: National Institute of Diabetes and Digestive and Kidney Diseases; 2012. Nortriptyline. 2020 Apr 5.

    Google Scholar 

  51. Tutka P, Zatonski W. Cytisine for the treatment of nicotine addiction: from a molecule to therapeutic efficacy. Pharmacol Rep. 2006;58(6):777–98.

    CAS  Google Scholar 

  52. Chapter 9: Gender, women, and the tobacco epidemic. In: Samet JM, Yoon S-Y, editors. Pregnancy and postpartum smoking cessation. World Health Organization; 2010. p. 175–88. ISBN 978 92 4 159951 1.

    Google Scholar 

  53. Scheffers-van Schayck T, Tuithof M, Otten R, et al. Smoking behavior of women before, during, and after pregnancy: indicators of Smoking, quitting, and relapse. Eur Addict Res. 2019;25(3):132–44. https://doi.org/10.1159/000498988.

    Article  Google Scholar 

  54. Grangé G, Berlin I, Bretelle F, et al. CNGOF-SFT expert report and guidelines for smoking management during pregnancy-short text. Gynecol Obstet Fertil Senol. 2020. pii: S2468-7189(20)30158-6. https://doi.org/10.1016/j.gofs.2020.04.005.

  55. Diamanti A, Papadakis S, Schoretsaniti S, et al. Smoking cessation in pregnancy: an update for maternity care practitioners. Tob Induc Dis. 2019;17:57. https://doi.org/10.18332/tid/109906. eCollection 2019.

    Article  CAS  Google Scholar 

  56. Lumley J, Chamberlain C, Dowswell T, et al. Interventions for promoting smoking cessation during pregnancy. Cochrane Database Syst Rev. 2009;(3):CD001055. https://doi.org/10.1002/14651858.CD001055.pub3. Update in: Cochrane Database Syst Rev. 2013;10:CD001055.

  57. Wen X, Eiden RD, Justicia-Linde FE, et al. A multicomponent behavioral intervention for smoking cessation during pregnancy: a nonconcurrent multiple-baseline design. Transl Behav Med. 2019;9(2):308–18. https://doi.org/10.1093/tbm/iby027.

    Article  Google Scholar 

  58. Claire R, Chamberlain C, Davey MA, et al. Pharmacological interventions for promoting smoking cessation during pregnancy. Cochrane Database Syst Rev. 2020;3:CD010078. https://doi.org/10.1002/14651858.CD010078.pub3.

    Article  Google Scholar 

  59. Blanc J, Koch A. Pharmacotherapy for smoking cessation during pregnancy - CNGOF-SFT expert report and guidelines for smoking management during pregnancy. Gynecol Obstet Fertil Senol. 2020. pii: S2468-7189(20)30143-4.; https://doi.org/10.1016/j.gofs.2020.03.030.

  60. Park JS, Lee SH, Lee GH, Yang MR, Park I, Oh B. Multidisciplinary approach to smoking cessation in late adolescence: a pilot study. Glob Pediatr Health. 2020;7:2333794X20944656. https://doi.org/10.1177/2333794X20944656.

    Article  Google Scholar 

  61. Peterson AV Jr, Marek PM. Late smoking relapse among adolescent quitters. Addict Behav. 2017;65:171–3.

    Article  Google Scholar 

  62. Tran TPT, Park J, Park E, Shin SH, Paek YJ, Kim YH, Lim MK. Effect of additional motivational interviewing on smoking abstinence for 1-year among Korean adolescents: results from a comparative retrospective study in quitline. Int J Environ Res Public Health. 2020;17(21):8025. https://doi.org/10.3390/ijerph17218025.

    Article  Google Scholar 

  63. Fotiou A, Stavrou M, Kokkevi A. Smoking cessation among adolescents. In: Behrakis PK, Vardavas CI, Papadakis S, editors. Tobacco cessation guidelines for high risk groups (TOB.g). Athens: European Network for Smoking Prevention; 2017. http://tob-g.eu/wp-content/uploads/TOB-G-BOOK-DIGITAL-VERSION.pdf

  64. Trofor AC, Papadakis S, Lotrean L, et al. Tobacco treatment guideline for high risk groups: a pilot study in patients with chronic obstructive pulmonary disease. Tob Induc Dis. 2018;16:13. https://doi.org/10.18332/tid/85944.

    Article  Google Scholar 

  65. van Eerd EA, van der Meer RM, van Schayck OC, Kotz D. Smoking cessation for people with chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2016;2016(8):CD010744. https://doi.org/10.1002/14651858.CD010744.pub2.

    Article  Google Scholar 

  66. Behrakis P. TOB-G: tobacco cessation guidelines for high risk populations. Tob Prev Cessat. 2016;2(April Supplement):39. https://doi.org/10.18332/tpc/62428.

    Article  Google Scholar 

  67. Avallone KM, Kimberly M, McLeish AC, et al. Asthma and its relation to smoking behavior and cessation motives among adult daily smokers. J Health Psychol. 2012;18(6):788–99. https://doi.org/10.1177/1359105312456322.

    Article  Google Scholar 

  68. Chatkin JM, Dullius CR. The management of asthmatic smokers. Asthma Res Pract. 2016;2:10. https://doi.org/10.1186/s40733-016-0025-7.

    Article  Google Scholar 

  69. Perret JL, Bonevski B, McDonald CF, Abramson MJ. Smoking cessation strategies for patients with asthma: improving patient outcomes. J Asthma Allergy. 2016;9:117–28. https://doi.org/10.2147/JAA.S85615.

    Article  Google Scholar 

  70. Tonnesen P, Pisinger C, Hvidberg S, et al. Effects of smoking cessation and reduction in asthmatics. Nicotine Tob Res. 2005;7:139–48. https://doi.org/10.1080/14622200412331328411.

    Article  Google Scholar 

  71. Holland JM, Holland E, Chen Y, Brown SA. Smoking history and cessation discussions in cancer patients receiving definitive radiotherapy: do we treat all patients equally? Tob Prev Cessat. 2020;6:31. https://doi.org/10.18332/tpc/120308.

    Article  Google Scholar 

  72. Benowitz NL, Pipe A, West R, et al. Cardiovascular safety of varenicline, bupropion, and nicotine patch in smokers: a randomized clinical trial. JAMA Intern Med. 2018;178(5):622–31. https://doi.org/10.1001/jamainternmed.2018.0397.

    Article  Google Scholar 

  73. Evins AE, Benowitz NL, West R, et al. Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with psychotic, anxiety, and mood disorders in the EAGLES trial. J Clin Psychopharmacol. 2019;39(2):108–16. https://doi.org/10.1097/JCP.0000000000001015.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Kocaeli University, School of Medicine, Department of Pulmonary Diseases, Kocaeli, Turkey

    Serap Argun Baris

  2. Cyprus International University Department of Pulmonary Diseases Nicosia, Turkish Republic of North Cyprus (TRNC), Nicosia, Cyprus

    Fusun Yildiz

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  1. Serap Argun Baris
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  2. Fusun Yildiz
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Correspondence to Serap Argun Baris .

Editor information

Editors and Affiliations

  1. Department of Otorhinolaryngology, Eskişehir Osmangazi University, Eskisehir, Türkiye

    Cemal Cingi

  2. Department of Pulmonology, Celal Bayar University, Manisa, Türkiye

    Arzu Yorgancıoğlu

  3. Department of Otorhinolaryngology, Kırıkkale University, Kırıkkale, Türkiye

    Nuray Bayar Muluk

  4. Federal University of Bahia School of Medicine and ProAR Foundation, Salvador - Bahia, Brazil

    Alvaro A. Cruz

Section Editor information

  1. Department of Pulmonology, Gazi University School of Medicine, Ankara, Turkey

    I. K. Oguzulgen MD

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Argun Baris, S., Yildiz, F. (2023). Nicotine Dependence and Recommendations for Smoking Cessation. In: Cingi, C., Yorgancıoğlu, A., Bayar Muluk, N., Cruz, A.A. (eds) Airway Diseases. Springer, Cham. https://doi.org/10.1007/978-3-031-22483-6_98-1

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