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Bioactive Compounds of Royal Poinciana (Delonix regia (Hook.) Raf.)

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Bioactive Compounds in Underutilized Vegetables and Legumes

Part of the book series: Reference Series in Phytochemistry ((RSP))

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Abstract

The plant Delonix regia (Bojer ex Hook) Raffin, family Caesalpiniaceae, grows in Madagascar, India, Africa, and Northern Australia. The plant is well known as flame of forest or royal poinciana and has been extensively used traditionally or in Ayurveda for the treatment of various diseases including jaundice, ulcer, wound, arthritis, malarial, emetic, infection, inflammatory, pain, and diarrhea. Phytochemical studies show that plant D. regia contains flavonoids, tannins, saponins, sterols, steroids, alkaloids, triterpenoids, anthocyanins, carotene hydrocarbons as bioactive secondary metabolites. In this chapter, we present an up-to-date compilation according to the latest references on various phytochemical constituents including bioactive as well as pharmacological effects.

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References

  1. Sen S, Chakraborty R (2017) Revival, modernization and integration of Indian traditional herbal medicine in clinical practice: importance, challenges and future. J Tradit Complement Med 7(2):234–244

    Article  PubMed  Google Scholar 

  2. Patwardhan B, Warude D, Pushpangadan P, Bhatt N (2005) Ayurveda and traditional Chinese medicine: a comparative overview. Evid Based Complement Alternat Med 2(4):465–473

    Article  PubMed  PubMed Central  Google Scholar 

  3. Pan SY, Zhou SF, Gao SH, Yu ZL, Zhang SF, Tang MK, Sun JN, Ma DL, Han YF, Fong WF, Ko KM (2013) New perspectives on how to discover drugs from herbal medicines: CAM's outstanding contribution to modern therapeutics. Evid Based Complement Alternat Med:2013

    Google Scholar 

  4. Veeresham C (2012) Natural products derived from plants as a source of drugs. J Adv Pharm Technol Res 3(4):200–201

    Article  PubMed  PubMed Central  Google Scholar 

  5. Shweta J, Ankur V, Pankaj K (2011) Pharmacognostic and phytochemical investigations of the leaves of Zizyphus xylopyrus (retz) willd. Int J Pharm Pharm Sci 3(2):122–125

    Google Scholar 

  6. Shweta J, Sourabh J, Nagendra SC, Ankur V (2019) Gastrointestinal protective effect of Zizyphus xylopyrus (Retz) wild leaf extract against indomethacin and HCl-EtOH induced ulcers. Curr Trad Med 5(2):140–146

    Article  CAS  Google Scholar 

  7. Modi A, Mishra V, Bhatt A, Jain A, Mansoori MH, Gurnany E, Kumar V (2016) Delonix regia (Bojer ex Hook) Raffin: historic perspectives and modern phytochemical and pharmacological researches. Chin J Nat Med 14(1):1–9

    Google Scholar 

  8. Cowen DV (1984) Flowering trees and shrubs in India. Thacker and Co. Ltd, Bombay

    Google Scholar 

  9. Orwa C, Mutua A, Kindt R, Jamnadass R, Simons A (2013) Delonix regia. Agroforestry

    Google Scholar 

  10. Rahmatullah M, Haque MR, Kamrul IS, Jamal F, Bashar AM, Ahmed R (2010) A survey on the use of medicinal plants by folk medicinal practitioners in three areas of pirojpur district, Bangladesh. Am-Eurasian J Sustain Agric 4:247–259

    Google Scholar 

  11. Halim MA, Chowdhury MSH, Wadud AI, Uddin MS, Sarker SK, Uddin MB (2007) The use of plants in traditional health care practice of the Shaiji community in south western Bangladesh. J Trop Forest Sci 19:168–175

    Google Scholar 

  12. Rekha D, Tamil SS, Bharathidasan R, Panneerselvam A, Ilakkiya R, Jayapal R (2013) Study of medicinal plants used from Koothanoallur and Marakkadai, Thiruvarur district of Tamil Nadu, India. Hygeia J Drugs Med 5:164–170

    Google Scholar 

  13. Khare CP (2007) Indian medicinal plants-an illustrated dictionary. Springer Science & Business Media, New York

    Book  Google Scholar 

  14. Chou CH, Leu LL (1992) Allelopathic substances and interactions of Delonix regia (Boj) Raf. J Chem Ecol 18(12):2285–2303

    Article  CAS  PubMed  Google Scholar 

  15. Fowler DG (2006) Traditional fever remedies: a list of Zambian plants. Kirkia 18(19):35–48

    Google Scholar 

  16. Ahirrao RA, Patel MR, Hamid S, Patil JK (2011) In vitro anthelmintic property of Gulmohar flowers against Pheritima posthuma. Pharmacol Online 2:728–732

    Google Scholar 

  17. Ahmed J, Sunil N, Vipul D, Anuja P, Sagar K, Subodh P, Subhash M, Shashikant P (2011) Hepatoprotective activity of methanol extract of aerial parts of Delonix regia. Phytopharmacol 1(5):118–122

    Google Scholar 

  18. Deepa B, Remadevi OK (2011) Larvicidal activity of the flowers of Delonix regia (Bojer ex Hook.) Rafin. (Fabales: Fabaceae) against the teak defoliator, Hyblaeapuera Cramer. Curr Biotica 5(2):237–240

    Google Scholar 

  19. Vidyasagar GM, Kumar P (2007) Traditional herbal remedies for gynecological disorders in women of Bidar district, Karnataka, India. Fitoterapia 78(1):48–51

    Article  CAS  PubMed  Google Scholar 

  20. Khursheed R, Naz A, Naz E, Sharif H, Rizwani GH (2012) Antibacterial, antimycelial and phytochemical analysis of Ricinus communis Linn, Trigonella foenumgrecum Linn and Delonix regia (Bojer ex Hook.) Raf of Pakistan. Rom Biotechnol Lett 17(3):7237–7244

    Google Scholar 

  21. Shiramane RS, Biradar KV, Chivde BV, Shambhulingayya HM, Goud V (2011) In vivo antidiarrhoeal activity of ethanolic extract of Delonix regia flowers in experimental induced diarrhoea in wistar albino rats. Int J Res Pharm Chem 1(3):442–447

    Google Scholar 

  22. Saloni S, Saroj A (2015) Phytochemicals and pharmaceutical potential of Delonix regia (Bojer ex Hook) Raf: a review. Int J Pharm Pharm Sci 7(8):17–29

    Google Scholar 

  23. Husain A, Khan MA, Saxena A, Fatima FT, Sharma G, Goud V (2012) Study of wound healing activity of Delonix regia flowers in experimental animal models. Am J Pharm Tech Res 2(2):380–390

    Google Scholar 

  24. Rani PMJ, Kannan PSM, Kumaravel S (2011) Screening of antioxidant activity, total phenolics and gas chromatography and mass spectrometer (GC-MS) study of Delonix regia. Afr J Biochem Res 5(12):341–347

    Google Scholar 

  25. Rahman MM, Hasan MN, Das AK, Hossain T, Jahan R, Khatun A, Rahmatullah M (2011) Effect of Delonix regia leaf extract on glucose tolerance in glucose induced- hyperglycemic mice. Afr J Tradit Complement Altern Med 8(1):34–36

    CAS  PubMed  Google Scholar 

  26. Shewale VD, Deshmukh TA, Patil LS, Patil VR (2012) Anti-inflammatory activity of Delonix regia (Boj. Ex. Hook). Adv Pharmacol Sci 5(Suppl 3):1–4

    Google Scholar 

  27. Chandrawat P, Singh D, Sharma SK, Sharma R (2012) Cytological studies of two species of genus Delonix. Int J Pharma Sci Res 3(2):596–599

    Google Scholar 

  28. Roohani N, Hurrell R, Kelishadi R, Schulin R (2013) Zinc and its importance for human health: an integrative review. J Res Med Sci 18(2):144–157

    PubMed  PubMed Central  Google Scholar 

  29. Sofowora A, Ogunbodede E, Onayade A (2013) The role and place of medicinal plants in the strategies for disease prevention. Afr J Tradit Complement Altern Med 10(5):210–229

    PubMed  PubMed Central  Google Scholar 

  30. Oyedeji OA, Azeez LA, Osifade BG (2017) Chemical and nutritional compositions of flame of forest (Delonix regia) seeds and seed oil. South African J Chem 70:16–20

    Article  CAS  Google Scholar 

  31. Sama K, Xavier V, Raja A (2011) Preliminary phytochemical screening of root bark of Delonix regia. Int J Pharm Life Sci 2(10):42–43

    Google Scholar 

  32. Kumar AR, Shaik R, Yeshwanth D (2013) Phytochemical evaluation of Delonix regia, Samaneasaman, Bauhinia variegatga. Int J Res Pharm Chem 3(4):768–772

    Google Scholar 

  33. Adje FA, Lozano YF, Le Gerneve C, Lozano PR, Meudec E, Adima AA, Gaydou EM (2012) Phenolic acid and flavonol water extracts of Delonix regia red flowers. Ind Crop Prod 37(1):303–310

    Article  CAS  Google Scholar 

  34. Jungalwala FB, Cama HR (1962) Carotenoids in Delonix regia (Gul Mohr) flower. Biochem J 85(1):1–8

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  35. Sharma RA, Chandrawat P, Sharma S, Sharma D, Sharma B, Singh D (2010) Efficacy of Delonix regia Rafin (Syn. Poinciana regia Bojer ex. Hook) for potential antifungal activity. Bioscan 5(3):441–444

    Google Scholar 

  36. Meli R, Autore G, Di Carlo G, Capasso F (1990) Inhibitory action of Quercetin on intestinal transits in mice. Phytother Res 4:201–202

    Article  CAS  Google Scholar 

  37. Jahan I, Rahman M, Rahman M, Kaisar M, Islam M, Wahab A, Rashid M (2010) Chemical and biological investigations of Delonix regia (Bojer ex Hook.) Raf. Acta Pharma 60(2):207–215

    CAS  Google Scholar 

  38. Ragasa CY, Hofilena JG (2011) Antimicrobial coumarin derivative from Delonix regia. Manila J Sci 7(1):7–11

    Google Scholar 

  39. Mariajancyrani J, Chandramohan G, Ravikumar R (2013) Isolation and identification of phytoconstituents from Delonix regia leaves. Int J Pharm Pharma Sci 5(4):671–674

    CAS  Google Scholar 

  40. Mohamed ES, Ek-Sayed AM, Salama MM, Amany AS (2011) Hepatoprotective and cytotoxic activities of Delonix regia flower extracts. Pharmacog J 3(19):49–56

    Article  CAS  Google Scholar 

  41. Alves DT, Vasconcelos IM, Oliveira JT, Farias LR, Dias SC, Chiarello MD, Maria-Neto S, Franco OL (2009) Identification of four novel members of Kunitz-like α-amylase inhibitors family from Delonix regia with activity toward coleopteran insects. Pesticide Biochem Physio 195(3):166–172

    Article  CAS  Google Scholar 

  42. Krauchenco S, Pando SC, Marangoni S, Polikarpov I (2003) Crystal structure of the Kunitz (STI)-type inhibitor from Delonix regia seeds. Biochem Biophys Res Comm 312(4):1303–1308

    Article  CAS  PubMed  Google Scholar 

  43. Chai WM, Shi Y, Feng HL, Qiu L, Zhou HC, Deng ZW, Yan CL, Chen QX (2012) NMR, HPLC-ESI-MS, and MALDI-TOF MS analysis of condensed tannins from Delonix regia (Bojer ex Hook.) Raf. and their bioactivities. J Agric Food Chem 60(19):5013–5022

    Article  CAS  PubMed  Google Scholar 

  44. Shabir G, Anwar F, Sultana B, Khalid ZM, Afzal M, Khan QM, Ashrafuzzaman M (2011) Antioxidant and antimicrobial attributes and phenolics of different solvent extracts from leaves, flowers and bark of gold mohar Delonix regia (Bojer ex Hook.) Raf. Molecules 16:7302–7319

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  45. Vargas AMM, Garcia CA, Reis EM, Lenzi E, Costa WF, Almeida VC (2010) NaOH-activated carbon from flamboyant (Delonix regia) pods: optimization of preparation conditions using central composite rotatable design. Chem Eng J 162:43–50

    Article  CAS  Google Scholar 

  46. Barua RK, Barua AB (1966) Oxidation of zeaxanthin isolation and properties of 3-hydroxyretinene. Biochem J 101(1):250–255

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  47. Ebrahim N, Rastrelli L (2013) Comparative study of anthocyanins content of some selected Yemeni plants. J Pharm Phytother 1(5):1–4

    Google Scholar 

  48. Azab SS, Abdel-Daim M, Eldahshan OA (2013) Phytochemical, cytotoxic, hepatoprotective and antioxidant properties of Delonix regia leaves extract. Med Chem Res 22(9):4269–4277

    Article  CAS  Google Scholar 

  49. El-Sayed AM, Ezzat SM, Salama MM, Sleem AA (2011) Hepatoprotective and cytotoxic activities of Delonix regia flower extracts. Pharmacog J 3(19):49–56

    Article  CAS  Google Scholar 

  50. Shanmukha I, Patel H, Patel J, Riyazunnisa (2011) Quantification of total phenol and flavonoid content of Delonix regia flowers. Int J Chem Tech Res 3(1):280–283

    CAS  Google Scholar 

  51. Hoasamani KM, Hosamani SK (1995) Component fatty acids of Delonix regia seed oil: a source of 7-(2-Octacyclopropen- 1-yI) heptanoic acid and 8-(2-OctacycIopropen-1-yl) octanoic acid. Eur J Lipid Sci Tech 97(11):420–422

    Google Scholar 

  52. Tamaki Y, Teruya T, Tako M (2010) The chemical structure of galactomannan isolated from seeds of Delonix regia. Biosci Biotechnol Biochem 74(5):1110–1112

    Article  CAS  PubMed  Google Scholar 

  53. Adewuyi A, Oderinde RA, Rao BV, Prasad RB, Anjaneyulu B (2010) Chemical component and fatty acid distribution of Delonix regia and Peltophorum pterocarpum seed oils. Food Sci Technol Res 16(6):565–570

    Article  CAS  Google Scholar 

  54. Kapoor VP (1972) A galactomannan from the seeds of Delonix regia. Phytochemistry 11(3):1129–1132

    Article  CAS  Google Scholar 

  55. Sharma S, Arora S (2015) Phytochemicals and pharmaceutical potential of Delonix regia (bojer ex Hook) Raf a review. Int J Pharm Pharm Sci 7:21–33

    Google Scholar 

  56. Salem MZM (2013) Evaluation of the antibacterial and antioxidant activities of stem bark extracts of Delonix regia and Erythrina Humeana grown in Egypt. J Forest Prod Ind 2(2):48–52

    Google Scholar 

  57. Aqil F, Ahmad I, Mehmood Z (2006) Antioxidant and free radical scavenging properties of twelve traditionally used Indian medicinal plants. Turk J Biol 30:177–183

    Google Scholar 

  58. Veigas JM, Narayan MS, Kotamballi N, Bhagyalakshmi N (2007) Antioxidative efficacies of floral petal extracts of Delonix regia Rafin. Int J Biomed Pharm Sci 1(1):73–82

    Google Scholar 

  59. Vivek MN, Swamy SHC, Manasa M, Pallavi S, Kambar Y, Asha MM, Chaithra M, Kekuda PTR, Mallikarjun N, Onkarappa R (2013) Antimicrobial and antioxidant activity of leaf and flower extract of Caesalpinia pulcherrima, Delonix regia and Peltaphorum ferrugineum. J Appl Pharm Sci 3(8):64–71

    Google Scholar 

  60. Subramanian SS, Malhotra A, Murti VVS (1966) Chemical examination of the barks of Delonix elata and D. regia. Curr Sci 35(17):437–438

    Google Scholar 

  61. Guerere M, Mondanand JM, Pajaniaye A, Guerere M, Mondanand JM, Pajaniaye A (1986) Physiochemical composition of seeds from several plants from the isle of Renion. Ann Falsif Expert Chem Toxicol 77(832):523–529

    Google Scholar 

  62. Rani JMJ, Chandramohan G, Kumaravel S (2012) Evaluation of antimicrobial activity of some garden plant leaves against Lactobacillus Sp, Streptococcus mitis, Candida albicans and Aspergillus niger. Afr J Basic Appl Sci 4(4):139–142

    Google Scholar 

  63. El Sherbeiny AE, Saleh NA, El Sissi HI (1971) Local plants as potential sources of tannins in Egypt part V (Lauraceae to Maliaceae). Qual Plant Mater Veg 20(4):285–296

    Article  Google Scholar 

  64. Xavier V, Raja A, Sama K (2012) Antibacterial and pharmacognostical evaluation of Delonix regia root bark. Int J Pharm Life Sci 3(4):1628–1630

    Google Scholar 

  65. Prakash M, Govindswamy C, Raju R, Beevi F (2013) Isolation and antibacterial activity of oleananoic acid acetate from Delonix regia leaves. J Pharm Res 6:423–425

    CAS  Google Scholar 

  66. Kim S, Lee H, Lee S, Yoon Y, Choi KH (2015) Antimicrobial action of oleanolic acid on Listeria monocytogenes, Enterococcus faecium, and Enterococcus faecalis. PLoS One 10(3):e0118800

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  67. Kekuda PTR, Sachidananda Swamy HC, Asha MM, Chaithra M, Vivek MN, Yoshoda PK (2014) Antibacterial activity of flower extract of Caesalpinia pulcherrima, Delonix regia and Peltaphorum ferrugineum against urinary tract pathogens. Int Res J Biol Sci 3(4):80–83

    Google Scholar 

  68. Sachidananda Swamy HC, Asha MM, Chaithra M, Vivek MN, YoshodaKambar PK (2014) Antibacterial activity of flower extract of Caesalpinia pulcherrima, Delonix regia and Peltaphorum ferrugineum against urinary tract pathogens. Int Res J Biol Sci 3(4):80–83

    Google Scholar 

  69. El-Gizawy HA, Alazzouni AS, El-Haddad AE (2018) Pharmacognostical and biological studies of Delonix regia growing in Egypt: HPLC profiles. Pharmacogn Commun 8(3):125–131

    Article  CAS  Google Scholar 

  70. Patra S, Meenakshi SM, Meenu M, Padma P, Brindha P (2016) Anti-inflammatory effects of royal poinciana through inhibition of toll-like receptor 4 signalling pathway. Int Immunopharmacol 34:199–211

    Article  CAS  PubMed  Google Scholar 

  71. Rozina P, Md Alam J, Md Rana S (2014) Antinociceptive and cytotoxic potential of ethanolic extract of Delonix regia (leaves). Ind J Pharm Bio Res 2(1):55–61

    Article  Google Scholar 

  72. Muruganandam S, Srinivasan K, Tandan SK, Lal J, Chandra S, Raviprakash V (2000) Anti-inflammatory and analgesic activities of some medicinal and aromatic plants. J Med Aromatic Plant Sci 22(4a):56–58

    Google Scholar 

  73. Pusapati MR, Jonnalagadda T, Kola PK, Yarlagadda AC, Guntuku G (2014) In vitro cytotoxic activity of hydro ethanolic extract of Delonix regia (Bojer ex. Hook.) flowers on cancer cell lines. Br J Pharm Res 4(4):443–452

    Article  Google Scholar 

  74. Chaturvedi D, Suhane N, Singh D, Chaturvedi N, Mishra A (2014) Anti-diabetic potential of Delonix regia. Int Res J Pharm 12(12):884–886

    Article  Google Scholar 

  75. Roy SP, Prajapati K, Gupta R, Bhadra D, Patel N, Batiwala A, Sonara G, Gheewala N, Kannadasan T (2013) Evaluation of anti-ulcer effects of ethanolic extract of Delonix regia flower. Ind J Res Pharm Biotech 1(3):440–445

    Google Scholar 

  76. Wang LS, Lee CT, Su WL, Huang SC, Wang SC (2016) Delonix regia leaf extract (DRLE): a potential therapeutic agent for cardio-protection. PLoS One 11(12):e0167768

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  77. Chitra V, Ilango K, Rajanandh MG, Soni D (2010) Evaluation of Delonix regia Linn. Flowers for antiarthritic and antioxidant activity in female wistar rats. Ann Bio Res 1(2):142–147

    Google Scholar 

  78. Fatmawaty F, Astuti H (2013) Antimalarial activity of Delonix regia on mice with Plasmodium berghei. J Nat Prod 6:61–66

    Google Scholar 

  79. Komal KS, Rana AC (2013) Herbal approaches for diarrhea: a review. Int Res J Pharm 4(1):313–318

    Google Scholar 

  80. Husain A, Saxena A, Fatima FT, Sharma G, Goud V, Khan MA (2012) Study of wound healing activity of Delonix regia flowers in experimental animal models. Am J Pharm Tech Res 2(2):380–390

    Google Scholar 

  81. Salman A, Toseef S, Mohtasheemul HM, Iqbal A (2012) Antiemetic activity of leaves extracts of five leguminous plants. Int J Res Ayur Pharm 3(2):251–253

    Google Scholar 

  82. Vennila J (2013) A study on antihemolytic activity of flavonoid fraction from the petals of Delonix regia. Int J Ethnomed Pharmacol Res 1(1):15–20

    Google Scholar 

  83. Velan SS, Prakash GJ, SindhanV RB (2012) Evaluation of diuretic activity of Delonix regia (Gulmohr) flowers in albino rats. Int J Res Pharm Sci 3(3):369–372

    Google Scholar 

  84. Aina SA, Banjo AD, Lawal OA, Okoh HI, Aina OO, Dedeke GA (2009) The toxicity of extracts of Tetrapleuratetraptera (Aridan), Delonix regia (flame of the Forest) and Raphiavinifera (raffia palm) on the larvae of Anopheles gambiae. Aca J Entomol 2(2):67–70

    Google Scholar 

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Authors and Affiliations

  1. Sir Madanlal Institute of Pharmacy, Etawah, Uttar Pradesh, India

    Shweta Jain

  2. Pharmacy College Saifai, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India

    Ankur Vaidya

  3. Department of Pharmaceutical Sciences, Dr. Hari Singh Gour University (A Central University), Sagar, Madhya Pradesh, India

    Nancy Jain

  4. School of Pharmacy, ITM (SLS) Baroda University, Vadodara, India

    Vimal Kumar

  5. Department of Pharmacy, Integrated Institute of Technology, New Delhi, India

    Anuj Modi

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  1. Shweta Jain
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  2. Ankur Vaidya
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  3. Nancy Jain
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  4. Vimal Kumar
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  5. Anuj Modi
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Editors and Affiliations

  1. Department of Botany, Karnatak University, Dharwad, Karnataka, India

    Hosakatte Niranjana Murthy

  2. Dept of Horticultural Science, Chungbuk National University, Cheonju, Korea (Republic of)

    Kee Yoeup Paek

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Jain, S., Vaidya, A., Jain, N., Kumar, V., Modi, A. (2021). Bioactive Compounds of Royal Poinciana (Delonix regia (Hook.) Raf.). In: Murthy, H.N., Paek, K.Y. (eds) Bioactive Compounds in Underutilized Vegetables and Legumes. Reference Series in Phytochemistry. Springer, Cham. https://doi.org/10.1007/978-3-030-44578-2_27-1

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  • DOI: https://doi.org/10.1007/978-3-030-44578-2_27-1

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  • Print ISBN: 978-3-030-44578-2

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