Abstract
Chlamydiae are obligate intracellular prokaryotes with a hexalaminar cell wall that, in contrast to other gram-negative bacteria, contains no peptidoglycan. As a major antigenic constitutent, their outer membrane contains a 10-kDa lipopolysaccharide (LPS) with a trisaccharide epitope specific for the family Chlamydiaceae (1). Another characteristic antigenic component is the major outer membrane protein (MOMP), a cysteine-rich protein of approx 40 kDa representing approx 60% of the weight of the outer membrane. This molecule harbors several genus- and species-specific antigenic determinants in the conserved regions and serovar-specific epitopes in variable domains (2).
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Sachse, K., Hotzel, H. (2003). Detection and Differentiation of Chlamydiae by Nested PCR. In: Sachse, K., Frey, J. (eds) PCR Detection of Microbial Pathogens. Methods in Molecular Biology™, vol 216. Humana Press. https://doi.org/10.1385/1-59259-344-5:123
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DOI: https://doi.org/10.1385/1-59259-344-5:123
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