Abstract
Detailed protocols for the preparation of CdSe nanocrystals coated with a multishell structure of ZnS and their surface modification based on the successive ion layer adsorption and reaction method are described. The first phase of the synthesis produces a hydrophobic surface consisting of a TOPO/HDA ligand mixture. This is followed by a surface modification of the quantum dots (QDs) with 3-mercaptopropionic acid by the phase transfer method. The modified QDs become soluble in aqueous systems such as water or buffers for further biological applications.
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Acknowledgements
This work was supported by a grant to A.S.M., the grant #PEST-OE/EQB/LA004/2011 and the project NTec/SQA/0131/2007 from the Fundação para a Ciência e Tecnologia.
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Miguel, A.S., Maycock, C., Oliva, A. (2012). Synthesis and Functionalization of CdSe/ZnS QDs Using the Successive Ion Layer Adsorption Reaction and Mercaptopropionic Acid Phase Transfer Methods. In: Soloviev, M. (eds) Nanoparticles in Biology and Medicine. Methods in Molecular Biology, vol 906. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61779-953-2_10
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DOI: https://doi.org/10.1007/978-1-61779-953-2_10
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