Abstract
Three experimental systems based on mouse models are currently used to study breast cancer: transgenic mice, carcinogen-induced models, and xenografts of breast cancers. Each of these models has advantages and limitations. This chapter focuses on xenotransplantation of breast cancers and reviews the techniques used so far in establishing this model, the advantages and limitations compared to other experimental systems, and finally, the technical questions that remain to be answered.
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Acknowledgment
R.M. is supported by the Breakthrough Breast Cancer Research Unit, Guy’s Hospital, King’s Health Partners, AHSC, London, UK.
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Cariati, M., Marlow, R., Dontu, G. (2011). Xenotransplantation of Breast Cancers. In: Cree, I. (eds) Cancer Cell Culture. Methods in Molecular Biology, vol 731. Humana Press. https://doi.org/10.1007/978-1-61779-080-5_38
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DOI: https://doi.org/10.1007/978-1-61779-080-5_38
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