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References
McDermott, K. W. and Luskin, M. B. (1995) The use of retroviral vectors in the study of cell lineage and migration during the development of the mammalian central nervous system, in Viral Vectors: Tools for Study and Genetic Manipulation of the Nervous System (Kaplitt, M. G. and Loewy, A. P., eds.), Academic, New York, pp. 411–433.
Sanes, J. R. (1989) Analysing cell lineage with a recombinant retrovirus. Trends Neurosci. 12, 21–28.
Compere, S. J., Baldacci, P. A., Sharpe, A. H., and Jaenisch, R. (1989) Retroviral transduction of the human c-Ha-ras-1 oncogene into midgestation mouse embryos promotes rapid epithelial hyperplasia. Mol. Cell. Biol. 9, 6–14.
Galileo, D. S., Majors, J., Horwitz, A. F., and Sanes, J. R. (1992) Retrovirally introduced antisense integrin RNA inhibits neuroblast migration in vivo. Neuron 9, 1117–1131.
Lillien, L. (1995) Changes in retinal cell fate induced by overexpression of EGF receptor. Nature 377, 158–162.
Stoker, A. W. (1993) Retroviral vectors, in Retroviral Vectors (Davidson, A. J., and Elliot, R. M., eds.), Oxford Press, Oxford, UK, pp. 171–197.
Danos, O. and Mulligan, R. C. (1988) Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges. Proc. Natl. Acad. Sci. USA 85, 6460–6464.
Pear, W. S., Nolan, G. P., Scott, M. L., and Baltimore, D. (1993) Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. USA 90, 8392–8396.
Sanes, J. R., Rubenstein, J. L., and Nicolas, J. F. (1986) Use of a recombinant retrovirus to study post implantation cell lineage in mouse embryos. EMBO J. 5, 3133–3142.
Price, J., Turner, D., and Cepko, C. (1987) Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer. Proc. Natl. Acad. Sci. USA 84, 156–160.
Luskin, M. B., Parnavelas, J. G., and Barfield, J. A. (1993) Neurons, astrocytes, and oligodendrocytes of the rat cerebral cortex originate from separate progenitor cells: an ultrastructural analysis of clonally related cells. J. Neurosci. 13, 1730–1750.
Mione, M. C., Danevic, C., Boardman, P., Harris, B., and Parnavelas, J. G. (1994) Lineage analysis reveals neurotransmitter (GABA or glutamate) but not calcium-binding protein homogeneity in clonally related cortical neurons. J. Neurosci. 14, 107–123.
Luskin, M. B. (1993) Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone. Neuron 11, 173–189.
Menezes, J. R. L., Smith, C. M., Nelson, K., and Luskin, M. B. (1995) The division of neuronal progenitor cells during migration in the neonatal mammalian forebrain. Mol. Cell. Neurosci. 6, 496–508.
Turner, D. L. and Cepko, C. L. (1987) A common progenitor for neurons and glia persists in rat retina late in development. Nature 328, 131–136.
Caggiano, M., Kauer, J. S., and Hunter, D. D. (1994) Globose basal cells are neu-ronal progenitors in the olfactory epithelium: a lineage analysis using a replication-incompetent retrovirus. Neuron 13, 339–352.
Schwob, J. E., Huard, J. M., Luskin, M. B., and Youngentob, S. L. (1994) Retroviral lineage studies of the rat olfactory epithelium. Chem. Senses 19, 671–682.
Bonnerot, C., Rocancourt, D., Briand, P., Grimber, G., and Nicolas, J. F. (1987) A beta-galactosidase hybrid protein targeted to nuclei as a marker for developmental studies. Proc. Natl. Acad. Sci. USA 84, 6795–6799.
Kotani, H., Newton III, P. B., Zhang, S., Chiang, Y. L., Otto, E., Weaver, L., Blaese, R. M., Anderson, W. F., and McGarrity, G. J. (1994) Improved methods of retroviral vector transduction and production for gene therapy. Hum. Gene Ther. 5, 19–28.
Acknowledgments
We thank Dr. John Parnavelas for advice pertaining to electron microscopy. The authors—research has been supported in part by grants from the National Institutes of Health to M. B. L (#NS28380) and to G. K. P (#AR43410) and by a Biomedical Scholars Award from the Pew Charitable Trusts and a Basic Research Grant from the March of Dimes Birth Defects Foundation to M. B. L.
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Luskin, M.B. (2008). Gene Transfer to the Rodent Embryo by Retroviral Vectors. In: Sharpe, P.T., Mason, I. (eds) Molecular Embryology. METHODS IN MOLECULAR BIOLOGY™, vol 461. Humana Press. https://doi.org/10.1007/978-1-60327-483-8_13
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