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Analysis of Genomic DNA with the UCSC Genome Browser

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Bioinformatics for DNA Sequence Analysis

Part of the book series: Methods in Molecular Biology ((MIMB,volume 537))

Abstract

Genomic DNA is being sequenced and annotated at a rapid rate, with terabases of DNA currently deposited in GenBank and other repositories. Genome browsers provide an essential collection of resources to visualize and analyze chromosomal DNA. The University of California, Santa Cruz (UCSC) Genome Browser provides annotations from the level of single nucleotides to whole chromosomes for four dozen metazoan and other species. The Genome Browser may be used to address a wide range of problems in bioinformatics (e.g., sequence analysis), comparative genomics, and evolution.

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Acknowledgments

I thank members of my lab (Erica Aronson, Laurence Frelin, Nathaniel Miller, Elisha Roberson, Asha Shah, Jason Ting) for helpful discussions, and N. Varg for comments on the manuscript. This work was supported in part by NIH grants HD046598 and 24061HD.

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Authors and Affiliations

  1. Department of Neurology, Kennedy Krieger Institute, Baltimore, MD, USA

    Jonathan Pevsner

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  1. Jonathan Pevsner
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Editors and Affiliations

  1. Dept. Bioquímica, Genética e Inmunología, Universidad de Vigo, Vigo, 36310, Spain

    David Posada

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© 2009 Humana Press, a part of Springer Science+Business Media, LLC

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Pevsner, J. (2009). Analysis of Genomic DNA with the UCSC Genome Browser. In: Posada, D. (eds) Bioinformatics for DNA Sequence Analysis. Methods in Molecular Biology, vol 537. Humana Press. https://doi.org/10.1007/978-1-59745-251-9_14

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  • DOI: https://doi.org/10.1007/978-1-59745-251-9_14

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-910-9

  • Online ISBN: 978-1-59745-251-9

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