Abstract
Th9 cells are a new subpopulation of CD4+ T helper cells, characterized by the expression of IL-9 that have been involved in type 2 immune responses, antitumor responses and autoimmune diseases. Here, we describe two different parasitic models frequently maintained in the laboratory where Th9 cells or IL-9 (the cytokine produced by Th9 cells) has been shown to play critical roles in pathogen clearance and immune response activation: the nematode Nippostrongylus brasiliensis and the trematode Schistosoma mansoni.
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Acknowledgment
We apologize to the researchers whose work could not be cited due to space limitations. This work was supported by the following grants from CONACYT (CB-2015-01-255287, S008-2015-2-261227) and DGAPA (IA202116-PAPIIT).
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Pinto, M.E.S., Licona-Limón, P. (2017). Th9 Cells and Parasitic Inflammation: Use of Nippostrongylus and Schistosoma Models. In: Goswami, R. (eds) Th9 Cells. Methods in Molecular Biology, vol 1585. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6877-0_18
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DOI: https://doi.org/10.1007/978-1-4939-6877-0_18
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