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Nutrition Intervention as a Preventative Approach to Fetal Alcohol Spectrum Disorder

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Fetal Alcohol Spectrum Disorder

Part of the book series: Neuromethods ((NM,volume 188))

Abstract

Despite known dangers of the teratogenic effects of alcohol on the fetus, resulting in fetal alcohol spectrum disorder (FASD), alcohol consumption during gestation continues to be prevalent in Canada. Optimal maternal nutrition status during pregnancy plays a crucial role for healthy birth outcomes. Alcohol consumption disrupts nutrition utilization leading to primary and secondary malnutrition, by displacing macronutrient-derived calories for alcohol-derived calories and disturbing metabolic processes of macro- and micronutrients. Inadequate maternal nutrition leads to decreased maternal plasma volume expansion and poor placental perfusion, which consequently impedes access to nutrients from the mother to the fetus. This exacerbates alcohol’s teratogenic damage leading to a plethora of negative health outcomes for an infant and a mother. Thus, optimizing maternal nutrition status through an intervention or prevention is strategy paramount when prenatal alcohol consumption is reported or suspected. A number of reports on prenatal and postnatal nutrient supplementation provide promising evidence for the nutrition intervention as a prevention strategy to mitigate FASD outcomes. An overview of nutrients discussed in this chapter can be utilized as a basis for the development of targeted nutrition intervention for women at risk of carrying a child with FASD.

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Acknowledgments

This work was supported by Manitoba Liquor & Lotteries and University of Manitoba Graduate Fellowship. All authors read and approved the final manuscript.

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Authors and Affiliations

  1. Department of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, MB, Canada

    Olena Kloss & Miyoung Suh

  2. Division of Neurodegenerative Disorders, St. Boniface Hospital Albrechtsen Research Centre, Winnipeg, MB, Canada

    Olena Kloss & Miyoung Suh

  3. Canadian Centre for Agri-Food Research in Health and Medicine, St. Boniface Hospital Albrechtsen Research Centre, Winnipeg, MB, Canada

    Olena Kloss & Miyoung Suh

  4. Department of Radiodiagnostics and Radiotheraopy, St. Petersburg North-Western State Medical University, St. Petersburg, Russia

    Lidia Sharova

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  1. Olena Kloss
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  2. Lidia Sharova
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  3. Miyoung Suh
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Correspondence to Miyoung Suh .

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Editors and Affiliations

  1. Dept. of Pediatrics and Child Health and Dept. of Biochem & Med. Genetics, University of Manitoba, Winnipeg, MB, Canada

    Albert E. Chudley

  2. Dept. of Biochem & Med. Genetics, Regenerative Medicine Program, University of Manitoba, Winnipeg, MB, Canada

    Geoff G. Hicks

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Kloss, O., Sharova, L., Suh, M. (2022). Nutrition Intervention as a Preventative Approach to Fetal Alcohol Spectrum Disorder. In: Chudley, A.E., Hicks, G.G. (eds) Fetal Alcohol Spectrum Disorder. Neuromethods, vol 188. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2613-9_10

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  • DOI: https://doi.org/10.1007/978-1-0716-2613-9_10

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-2612-2

  • Online ISBN: 978-1-0716-2613-9

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